Immunothrombosis: Molecular Aspects and New Therapeutic Perspectives

Immunothrombosis: Molecular Aspects and New Therapeutic Perspectives

Thromboinflammation or immunothrombosis is a concept that explains the existing link between coagulation and inflammatory response present in many situations, such as sepsis, venous thromboembolism, or COVID-19 associated coagulopathy. The purpose of this review is to provide an overview of the curr...

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Veröffentlicht in:Journal of clinical medicine 2023-02, Vol.12 (4), p.1399
Hauptverfasser: Marcos-Jubilar, María, Lecumberri, Ramón, Páramo, José A
Format: Artikel
Sprache:eng
Schlagworte:
Analysis
Bacteria
Bacterial infections
Blood coagulation factors
Blood platelets
Care and treatment
Cytokines
Diagnosis
Gram-negative bacteria
Inflammation
Neutrophils
Pathogens
Physiology
Proteins
Sepsis
Thromboembolism
Thrombosis
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Beschreibung
Zusammenfassung:Thromboinflammation or immunothrombosis is a concept that explains the existing link between coagulation and inflammatory response present in many situations, such as sepsis, venous thromboembolism, or COVID-19 associated coagulopathy. The purpose of this review is to provide an overview of the current data regarding the mechanisms involved in immunothrombosis in order to understand the new therapeutic strategies focused in reducing thrombotic risk by controlling the inflammation.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm12041399