Hemophagocytic Lymphohistiocytosis Following COVID-19 Infection

Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been associated with multiple inflammatory symptoms involving several organ systems, including hematologic manifestations. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening s...

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Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2023-01, Vol.15 (1), p.e34307
Hauptverfasser: Molina, Guarina, Contreras, Rafael, Coombes, Kyle, Walgamage, Thilini, Perozo, Maria A, DesBiens, Martha T
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Sprache:eng
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Zusammenfassung:Coronavirus disease 2019 (COVID-19), caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), has been associated with multiple inflammatory symptoms involving several organ systems, including hematologic manifestations. Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening syndrome caused by excessive inflammation in the absence of immune regulation. We present the case of a patient with HLH secondary to dysregulated inflammatory response following COVID-19; we also describe the diagnostic and management challenges associated with the condition.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.34307