Impact of COVID‐19 on HIV late diagnosis in a specialized German centre

Background The ongoing COVID‐19 pandemic has been impeding HIV diagnosis and treatment worldwide. Data on the impact of COVID‐19 on late diagnosis (LD) in Germany are lacking. Here we present novel data of a single‐centre German HIV cohort assessing LD during COVID‐19. Methods This is a non‐interventional, single‐centre retrospective cohort assessing the rate of LD comparing HIV diagnoses pre‐COVID‐19 with those during the COVID‐19 pandemic. New diagnoses between 1 January 2019 and 1 February 2020 were classified as pre‐COVID‐19, and diagnoses between 1 February 2020 and 1 October 2021 were classified as during COVID‐19. Results Between 1 January 2019 and 1 October 2021, 75 patients presented with newly diagnosed HIV infection, 34 pre‐COVID‐19 and 41 during COVID‐19. LD increased to 83% (n = 34/41) during COVID‐19 versus 59% (n = 20/34) pre‐COVID‐19, and CDC stage C3 rose to 44% (n = 18) versus 27%. Hospitalization rate increased to 49% (n = 20) during COVID‐19 versus 29% pre‐COVID‐19, and 12% (n = 5) presented with HIV‐associated neurological disease, whereas none were observed in the pre‐COVID‐19 group. The incidence of LD (p = 0.020), CD4 count