From Bench to Bedside in Rheumatoid Arthritis from the "2022 GISEA International Symposium"

From Bench to Bedside in Rheumatoid Arthritis from the "2022 GISEA International Symposium"

While precision medicine is still a challenge in rheumatic disease, in recent years many advances have been made regarding pathogenesis, the treatment of inflammatory arthropathies, and their interaction. New insight into the role of inflammasome and synovial tissue macrophage subsets as predictors...

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Veröffentlicht in:Journal of clinical medicine 2023-01, Vol.12 (2), p.527
Hauptverfasser: Vitale, Antonio, Alivernini, Stefano, Caporali, Roberto, Cassone, Giulia, Bruno, Dario, Cantarini, Luca, Lopalco, Giuseppe, Rossini, Maurizio, Atzeni, Fabiola, Favalli, Ennio Giulio, Conti, Fabrizio, Gremese, Elisa, Iannone, Florenzo, Ferraccioli, Gian Franco, Lapadula, Giovanni, Sebastiani, Marco
Format: Artikel
Sprache:eng
Schlagworte:
Adenosine triphosphate
Alzheimer's disease
Clinical medicine
Fever
Genes
Immune system
Inflammation
Inflammatory diseases
Mitochondrial DNA
Mutation
Pathogenesis
Potassium
Review
Rheumatism
Rheumatoid arthritis
Rheumatology
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Zusammenfassung:While precision medicine is still a challenge in rheumatic disease, in recent years many advances have been made regarding pathogenesis, the treatment of inflammatory arthropathies, and their interaction. New insight into the role of inflammasome and synovial tissue macrophage subsets as predictors of drug response give hope for future tailored therapeutic strategies and a personalized medicine approach in inflammatory arthropathies. Here, we discuss the main pathogenetic mechanisms and therapeutic approaches towards precision medicine in rheumatoid arthritis from the 2022 International GISEA/OEG Symposium.
ISSN:2077-0383
2077-0383
DOI:10.3390/jcm12020527