Differential infectivity and division of Toxoplasma gondii in human peripheral blood leukocytes

When tachyzoites were incubated with human peripheral blood leukocytes in vitro, more monocytes and dendritic cells than neutrophils or lymphocytes were infected. Although tachyzoites were able to divide in each of these cell types, monocytes and dendritic cells were more permissive to rapid tachyzo...

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Veröffentlicht in:Infection and immunity 2000-08, Vol.68 (8), p.4822-4826
Hauptverfasser: CHANNON, J. Y, SEGUIN, R. M, KASPER, L. H
Format: Artikel
Sprache:eng
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Zusammenfassung:When tachyzoites were incubated with human peripheral blood leukocytes in vitro, more monocytes and dendritic cells than neutrophils or lymphocytes were infected. Although tachyzoites were able to divide in each of these cell types, monocytes and dendritic cells were more permissive to rapid tachyzoite division than neutrophils or lymphocytes.
ISSN:0019-9567
1098-5522
DOI:10.1128/IAI.68.8.4822-4826.2000