Somatostatin Receptor-negative and Fluorodeoxyglucose-positron Emission Tomography-positive Lung Neuroendocrine Tumor G1 Exhibiting Cyclic Cushing's Syndrome

Localization of ectopic cyclic Cushing's syndrome, which causes life-threatening complications, is challenging. A 70-year-old woman showed cyclic hypokalemia and hyperglycemia and was diagnosed with cyclic ectopic Cushing's syndrome. Although somatostatin-receptor scintigraphy failed to lo...

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Veröffentlicht in:Internal Medicine 2022, pp.9238-21
Hauptverfasser: Nomura, Chiaki, Nakano, Yujiro, Tanaka, Takeo, Shima, Kosuke Robert, Kometani, Mitsuhiro, Kanamori, Takehiro, Ikeda, Hiroko, Takeshita, Yumie, Yoneda, Takashi, Takamura, Toshinari
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Sprache:eng
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Zusammenfassung:Localization of ectopic cyclic Cushing's syndrome, which causes life-threatening complications, is challenging. A 70-year-old woman showed cyclic hypokalemia and hyperglycemia and was diagnosed with cyclic ectopic Cushing's syndrome. Although somatostatin-receptor scintigraphy failed to localize the responsible tumor, fluorodeoxyglucose-positron emission tomography (FDG-PET) showed the uptake of tracer in a lung tumor. Lobectomy resulted in remission. The resected ACTH-producing neuroendocrine tumor had Ki-67
ISSN:0918-2918
1349-7235
DOI:10.2169/internalmedicine.9238-21