Detection of skin thickness and density in healthy Chinese people by using high‐frequency ultrasound

Objectives Due to a recent development of high‐frequency ultrasound (HFUS) systems, it is easier to realize high‐resolution in vivo imaging of the biological tissues. The object of this study was to map the thickness and echo density of skin layers in healthy Chinese people and assess the influence of gender, age, and region on it. Methods A total of 189 volunteers (85 male, 104 female) with age range of 22–75‐year old (mean age of 41.2‐year old) were enrolled. The thickness and density of the epidermis and dermis layer were detected by high‐frequency (22 or 75 MHz) ultrasonography at 13 different anatomical sites, including the forehead, cheeks, flexor and extensor forearms, flexor and extensor upper arms, inner and outer legs, inner and outer thighs, back, and abdomen. Results The thickness and density of epidermis/dermis between different anatomical sites were statistically significant (p