COVID-19 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of SARS-CoV-2 Pre-Transplant

COVID-19 pandemic has led to significant morbidity and mortality across the world. Lung Transplant (LT) is a viable option for a few with COVID-19 related lung disease. Who to transplant and when to transplant, has been the major question impacting the transplant community given the novelty of SARS-...

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Veröffentlicht in:Mayo Clinic proceedings. Innovations, quality & outcomes quality & outcomes, 2023-01
Hauptverfasser: Shah, Sadia Z., Alvarez, Francisco G., Sanghavi, Devang K., Franco-Moreno, Pablo, Isha, Shahin, Marquez, Chris, Libertin, Claudia, Guru, Pramod K., Sareyyupoglu, Basar, Pham, Si M.
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container_title Mayo Clinic proceedings. Innovations, quality & outcomes
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creator Shah, Sadia Z.
Alvarez, Francisco G.
Sanghavi, Devang K.
Franco-Moreno, Pablo
Isha, Shahin
Marquez, Chris
Libertin, Claudia
Guru, Pramod K.
Sareyyupoglu, Basar
Pham, Si M.
description COVID-19 pandemic has led to significant morbidity and mortality across the world. Lung Transplant (LT) is a viable option for a few with COVID-19 related lung disease. Who to transplant and when to transplant, has been the major question impacting the transplant community given the novelty of SARS-CoV-2. We describe a pitfall of presumed prolonged shedding of SARS-CoV-2, in a patient with COVID-19-associated acute respiratory distress syndrome (CARDS), leading to COVID-19 pneumonia post-LT. This raise concerns that replication-competent SARS-CoV-2 virus can persist for months post-infection and can lead to re-infection of allograft in the future.
doi_str_mv 10.1016/j.mayocpiqo.2023.01.001
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title COVID-19 Causing Infection of Transplanted Lung Allograft: A Pitfall of Prolonged Shedding of SARS-CoV-2 Pre-Transplant
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