A rare case report: vaginal paraganglioma

Vaginal paraganglioma (VP), usually solitary and primary, is a rare adrenal type paraganglioma derived from the anterior neural crest, and can be classified as a functional or non-functional tumor. Only 10 cases of VP have been reported since 1955. Herein, we report an unusual case of a 39-year-old female VP patient with symptoms of hypercatecholaminism and a family history of hypertension. After preoperative control of blood pressure with an alpha-receptor blocker, laparoscopic surgery was performed. The blood pressure fluctuated after touching the tumor intraoperatively, and the tumor was successfully and completely removed under anesthesia by surgery. Postoperative pathology confirmed the diagnosis. The clinical characteristics, auxiliary examination, morphological and pathological immunohistochemical characteristics, and perioperative treatment of VP are analyzed, and the literature of the previous 10 cases is reviewed, so as to help further understand VP and provide clinical guidance.