A comprehensive review of genomic perspectives of canine diseases as a model to study human disorders
The domestic dog has been given considerable attention as a system for investigating the genetics of human diseases. Population diversity and breed structure are unique features that make dogs particularly amenable to genetic studies. Dogs show distinguished features of breed-specific homogeneity, w...
Gespeichert in:
| Veröffentlicht in: | Canadian journal of veterinary research 2023-01, Vol.87 (1), p.3-8 |
|---|---|
| Hauptverfasser: | , , , , |
| Format: | Artikel |
| Sprache: | eng |
| Schlagworte: | |
| Online-Zugang: | Volltext |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | 8 |
|---|---|
| container_issue | 1 |
| container_start_page | 3 |
| container_title | Canadian journal of veterinary research |
| container_volume | 87 |
| creator | Kaur, Bhawanpreet Kaur, Jaswinder Kashyap, Neeraj Arora, Jaspreet Singh Mukhopadhyay, Chandra Sekhar |
| description | The domestic dog has been given considerable attention as a system for investigating the genetics of human diseases. Population diversity and breed structure are unique features that make dogs particularly amenable to genetic studies. Dogs show distinguished features of breed-specific
homogeneity, which is associated with striking interbreed heterogeneity. This review discusses the significance of studying the genetic maps, genome-wide association studies (GWAS), and usefulness of this species as an animal model. Most canine genetic disorders are similar to those of humans,
including inherited, psychiatric, and genetic disorders. In addition to revealing new candidate genes, canine models allow access to experimental resources, such as cells, tissues, and even live animals, for research and intervention purposes. |
| format | Article |
| fullrecord | <record><control><sourceid>pubtec_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9808881</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><ingid>cvma/cjvr/2023/00000087/00000001/art00002</ingid><sourcerecordid>cvma/cjvr/2023/00000087/00000001/art00002</sourcerecordid><originalsourceid>FETCH-LOGICAL-i395t-a5f7acabb84aea4ee372985283e0ee6c7929e1bb192333a9e29588b1600889e23</originalsourceid><addsrcrecordid>eNp1kN1q3DAQhU1oaLZJX6HoBRbG0q4t3QSW0D8I7U17PYzl2V0ta8lIskv69JU3aWkvKgQazZz5mDlX1ao2Uq8NSPmqWoFWUGKAm-pNSicA2TZSva5uVNNAAxtYVbwTNgxj5CP75GYWkWfHP0TYiwP7MDgrRo5pZJtLNS15S955Fr1LTKmkqFwxhJ7PIgeR8tQ_ieM0kF8kIfal_a663tM58duX97b6_uH9t4dP68evHz8_7B7XTpltXtN235KlrtMbYtowq1YavZVaMTA3tjXScN11ZUelFBmWZqt1VzcAWpefuq3un7nj1A3cW_Y50hnH6AaKTxjI4b8V7454CDMaXQi6LoB3fwP-dP42rAi-PAucL_5kwlOYoi87obNo54FwMX3xHGfd-holSAW1BISNAux5T9M5Y6aIh5-YlpF3_wFeaPY0xwsD4XJ0-xJAjRTzEkj1C6Ejmaw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype></control><display><type>article</type><title>A comprehensive review of genomic perspectives of canine diseases as a model to study human disorders</title><source>MEDLINE</source><source>PubMed Central</source><source>Alma/SFX Local Collection</source><source>EZB Electronic Journals Library</source><creator>Kaur, Bhawanpreet ; Kaur, Jaswinder ; Kashyap, Neeraj ; Arora, Jaspreet Singh ; Mukhopadhyay, Chandra Sekhar</creator><creatorcontrib>Kaur, Bhawanpreet ; Kaur, Jaswinder ; Kashyap, Neeraj ; Arora, Jaspreet Singh ; Mukhopadhyay, Chandra Sekhar</creatorcontrib><description>The domestic dog has been given considerable attention as a system for investigating the genetics of human diseases. Population diversity and breed structure are unique features that make dogs particularly amenable to genetic studies. Dogs show distinguished features of breed-specific
homogeneity, which is associated with striking interbreed heterogeneity. This review discusses the significance of studying the genetic maps, genome-wide association studies (GWAS), and usefulness of this species as an animal model. Most canine genetic disorders are similar to those of humans,
including inherited, psychiatric, and genetic disorders. In addition to revealing new candidate genes, canine models allow access to experimental resources, such as cells, tissues, and even live animals, for research and intervention purposes.</description><identifier>ISSN: 0830-9000</identifier><identifier>EISSN: 1928-9022</identifier><identifier>PMID: 36606040</identifier><language>eng</language><publisher>Canada: Canadian Veterinary Medical Association</publisher><subject>Animals ; Breeding ; Dog Diseases - genetics ; Dogs ; Genome ; Genome-Wide Association Study - veterinary ; Genomics ; Humans ; Review</subject><ispartof>Canadian journal of veterinary research, 2023-01, Vol.87 (1), p.3-8</ispartof><rights>Copyright and/or publishing rights held by the Canadian Veterinary Medical Association.</rights><rights>Copyright and/or publishing rights held by the Canadian Veterinary Medical Association 2023</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808881/pdf/$$EPDF$$P50$$Gpubmedcentral$$H</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9808881/$$EHTML$$P50$$Gpubmedcentral$$H</linktohtml><link.rule.ids>230,314,723,776,780,881,53770,53772</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36606040$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Kaur, Bhawanpreet</creatorcontrib><creatorcontrib>Kaur, Jaswinder</creatorcontrib><creatorcontrib>Kashyap, Neeraj</creatorcontrib><creatorcontrib>Arora, Jaspreet Singh</creatorcontrib><creatorcontrib>Mukhopadhyay, Chandra Sekhar</creatorcontrib><title>A comprehensive review of genomic perspectives of canine diseases as a model to study human disorders</title><title>Canadian journal of veterinary research</title><addtitle>Can J Vet Res</addtitle><description>The domestic dog has been given considerable attention as a system for investigating the genetics of human diseases. Population diversity and breed structure are unique features that make dogs particularly amenable to genetic studies. Dogs show distinguished features of breed-specific
homogeneity, which is associated with striking interbreed heterogeneity. This review discusses the significance of studying the genetic maps, genome-wide association studies (GWAS), and usefulness of this species as an animal model. Most canine genetic disorders are similar to those of humans,
including inherited, psychiatric, and genetic disorders. In addition to revealing new candidate genes, canine models allow access to experimental resources, such as cells, tissues, and even live animals, for research and intervention purposes.</description><subject>Animals</subject><subject>Breeding</subject><subject>Dog Diseases - genetics</subject><subject>Dogs</subject><subject>Genome</subject><subject>Genome-Wide Association Study - veterinary</subject><subject>Genomics</subject><subject>Humans</subject><subject>Review</subject><issn>0830-9000</issn><issn>1928-9022</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2023</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp1kN1q3DAQhU1oaLZJX6HoBRbG0q4t3QSW0D8I7U17PYzl2V0ta8lIskv69JU3aWkvKgQazZz5mDlX1ao2Uq8NSPmqWoFWUGKAm-pNSicA2TZSva5uVNNAAxtYVbwTNgxj5CP75GYWkWfHP0TYiwP7MDgrRo5pZJtLNS15S955Fr1LTKmkqFwxhJ7PIgeR8tQ_ieM0kF8kIfal_a663tM58duX97b6_uH9t4dP68evHz8_7B7XTpltXtN235KlrtMbYtowq1YavZVaMTA3tjXScN11ZUelFBmWZqt1VzcAWpefuq3un7nj1A3cW_Y50hnH6AaKTxjI4b8V7454CDMaXQi6LoB3fwP-dP42rAi-PAucL_5kwlOYoi87obNo54FwMX3xHGfd-holSAW1BISNAux5T9M5Y6aIh5-YlpF3_wFeaPY0xwsD4XJ0-xJAjRTzEkj1C6Ejmaw</recordid><startdate>20230101</startdate><enddate>20230101</enddate><creator>Kaur, Bhawanpreet</creator><creator>Kaur, Jaswinder</creator><creator>Kashyap, Neeraj</creator><creator>Arora, Jaspreet Singh</creator><creator>Mukhopadhyay, Chandra Sekhar</creator><general>Canadian Veterinary Medical Association</general><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>5PM</scope></search><sort><creationdate>20230101</creationdate><title>A comprehensive review of genomic perspectives of canine diseases as a model to study human disorders</title><author>Kaur, Bhawanpreet ; Kaur, Jaswinder ; Kashyap, Neeraj ; Arora, Jaspreet Singh ; Mukhopadhyay, Chandra Sekhar</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-i395t-a5f7acabb84aea4ee372985283e0ee6c7929e1bb192333a9e29588b1600889e23</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2023</creationdate><topic>Animals</topic><topic>Breeding</topic><topic>Dog Diseases - genetics</topic><topic>Dogs</topic><topic>Genome</topic><topic>Genome-Wide Association Study - veterinary</topic><topic>Genomics</topic><topic>Humans</topic><topic>Review</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kaur, Bhawanpreet</creatorcontrib><creatorcontrib>Kaur, Jaswinder</creatorcontrib><creatorcontrib>Kashyap, Neeraj</creatorcontrib><creatorcontrib>Arora, Jaspreet Singh</creatorcontrib><creatorcontrib>Mukhopadhyay, Chandra Sekhar</creatorcontrib><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Canadian journal of veterinary research</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kaur, Bhawanpreet</au><au>Kaur, Jaswinder</au><au>Kashyap, Neeraj</au><au>Arora, Jaspreet Singh</au><au>Mukhopadhyay, Chandra Sekhar</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>A comprehensive review of genomic perspectives of canine diseases as a model to study human disorders</atitle><jtitle>Canadian journal of veterinary research</jtitle><addtitle>Can J Vet Res</addtitle><date>2023-01-01</date><risdate>2023</risdate><volume>87</volume><issue>1</issue><spage>3</spage><epage>8</epage><pages>3-8</pages><issn>0830-9000</issn><eissn>1928-9022</eissn><abstract>The domestic dog has been given considerable attention as a system for investigating the genetics of human diseases. Population diversity and breed structure are unique features that make dogs particularly amenable to genetic studies. Dogs show distinguished features of breed-specific
homogeneity, which is associated with striking interbreed heterogeneity. This review discusses the significance of studying the genetic maps, genome-wide association studies (GWAS), and usefulness of this species as an animal model. Most canine genetic disorders are similar to those of humans,
including inherited, psychiatric, and genetic disorders. In addition to revealing new candidate genes, canine models allow access to experimental resources, such as cells, tissues, and even live animals, for research and intervention purposes.</abstract><cop>Canada</cop><pub>Canadian Veterinary Medical Association</pub><pmid>36606040</pmid><tpages>6</tpages></addata></record> |
| fulltext | fulltext |
| identifier | ISSN: 0830-9000 |
| ispartof | Canadian journal of veterinary research, 2023-01, Vol.87 (1), p.3-8 |
| issn | 0830-9000 1928-9022 |
| language | eng |
| recordid | cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9808881 |
| source | MEDLINE; PubMed Central; Alma/SFX Local Collection; EZB Electronic Journals Library |
| subjects | Animals Breeding Dog Diseases - genetics Dogs Genome Genome-Wide Association Study - veterinary Genomics Humans Review |
| title | A comprehensive review of genomic perspectives of canine diseases as a model to study human disorders |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-22T20%3A10%3A22IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-pubtec_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=A%20comprehensive%20review%20of%20genomic%20perspectives%20of%20canine%20diseases%20as%20a%20model%20to%20study%20human%20disorders&rft.jtitle=Canadian%20journal%20of%20veterinary%20research&rft.au=Kaur,%20Bhawanpreet&rft.date=2023-01-01&rft.volume=87&rft.issue=1&rft.spage=3&rft.epage=8&rft.pages=3-8&rft.issn=0830-9000&rft.eissn=1928-9022&rft_id=info:doi/&rft_dat=%3Cpubtec_pubme%3Ecvma/cjvr/2023/00000087/00000001/art00002%3C/pubtec_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/36606040&rft_ingid=cvma/cjvr/2023/00000087/00000001/art00002&rfr_iscdi=true |