Neutralization of SARS-CoV-2 omicron after BBIBP-CorV and ZF2001 booster vaccination

The omicron variant carries a large number of mutations in the spike protein, with at least 15 mutations in the receptor-binding domain (RBD), the primary target of neutralizing antibodies [1]. In the comparison of the effects in booster dose between younger and older groups, there was no significant difference in neutralizing antibody levels between the group B and group A after BBIBP-CorV booster, and between the group D and group C at 28 days after ZF2001 booster(Table 1). ZR202112040005).Declaration of interest statement The authors declare that the research was conducted in the absence of any commercial or financial relationships that could be construed as a potential conflict of interest.Acknowledgements None.Appendix A Supplementary data The following is the Supplementary data to this article.Multimedia component 1Multimedia component 1Appendix A Supplementary data Supplementary data to this article can be found online at https://doi.org/10.1016/j.tmaid.2022.102531.