Molecular docking analysis and dynamics simulation of salbutamol with the monoamine oxidase B (MAO-B) enzyme

Molecular docking analysis and dynamics simulation of salbutamol with the monoamine oxidase B (MAO-B) enzyme

The monoamine oxidase B (MAO-B) enzyme is linked with Parkinson's disease. Therefore, it is of interest to document the molecular docking analysis and dynamics simulation of salbutamol, a well-known β2-adrenoceptor agonist, with the monoamine oxidase B (MAO-B) enzyme for further consideration i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Bioinformation 2022-03, Vol.18 (3), p.304-309
Hauptverfasser: Abdulhameed Odhar, Hasanain, Fadhil Hashim, Ahmed, Sami Humad, Suhad
Format: Artikel
Sprache:eng
Schlagworte:
Adrenergic receptors
Amine oxidase (flavin-containing)
Drug development
Enzymes
Molecular docking
Movement disorders
Neurodegenerative diseases
Oxidase
Parkinson's disease
Salbutamol
Simulation
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The monoamine oxidase B (MAO-B) enzyme is linked with Parkinson's disease. Therefore, it is of interest to document the molecular docking analysis and dynamics simulation of salbutamol, a well-known β2-adrenoceptor agonist, with the monoamine oxidase B (MAO-B) enzyme for further consideration in drug design and development.
ISSN:0973-2063
0973-8894
0973-2063
DOI:10.6026/97320630018304