Clinical and ultrasonography follow-up of five cases of calcinosis cutis successfully treated with intralesional sodium thiosulfate

Calcinosis cutis (CC) is characterized by deposit of calcium salts in the skin and subcutaneous tissue; its clinical presentation consists of indurated painful nodules, which can ulcerate and become superinfected. CC treatment remains a challenge, yet successful treatment with intralesional (IL) sod...

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Veröffentlicht in:Journal of ultrasound 2022-12, Vol.25 (4), p.995-1003
Hauptverfasser: Tubau, Carla, Cubiró, Xavier, Amat-Samaranch, Victoria, Garcia-Melendo, Cristina, Puig, Lluís, Roé-Crespo, Esther
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Sprache:eng
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Zusammenfassung:Calcinosis cutis (CC) is characterized by deposit of calcium salts in the skin and subcutaneous tissue; its clinical presentation consists of indurated painful nodules, which can ulcerate and become superinfected. CC treatment remains a challenge, yet successful treatment with intralesional (IL) sodium thiosulfate (STS) has been reported in several CC subtypes. Herein we are reporting on a case series of 5 patients with CC successfully treated with IL-STS. We describe the 18–22 MHz ultrasound characteristics of the lesions and on follow-up after treatment. Ultrasound imaging was useful in guiding IL-STS injections and confirming response to treatment.
ISSN:1876-7931
1971-3495
1876-7931
DOI:10.1007/s40477-022-00665-4