ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report

ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report

A 45-year-old female, a new case of acute promyelocytic leukemia (APL), received induction chemotherapy containing all- trans retinoic acid (ATRA) and idarubicin. On the sixth day of therapy, she developed sinus bradycardia and differentiation syndrome (DS). Electrolytes and cardiac imaging were nor...

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Veröffentlicht in:Journal of family medicine and primary care 2022-07, Vol.11 (7), p.3999-4001
Hauptverfasser: Rathod, Santosh Govind, Khan, Afaq Ahmad, Geelani, Sajad Ahmed, Roshan, Reshma, Bhat, Javid Rasool
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Case Report
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container_issue 7
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container_title Journal of family medicine and primary care
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creator Rathod, Santosh Govind
Khan, Afaq Ahmad
Geelani, Sajad Ahmed
Roshan, Reshma
Bhat, Javid Rasool
description A 45-year-old female, a new case of acute promyelocytic leukemia (APL), received induction chemotherapy containing all- trans retinoic acid (ATRA) and idarubicin. On the sixth day of therapy, she developed sinus bradycardia and differentiation syndrome (DS). Electrolytes and cardiac imaging were normal. The patient achieved normal sinus rhythm after ATRA was withheld, and DS was treated.
doi_str_mv 10.4103/jfmpc.jfmpc_1663_21
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title ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report
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