ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report

ATRA-induced bradycardia in a case of acute promyelocytic leukemia: A case report

A 45-year-old female, a new case of acute promyelocytic leukemia (APL), received induction chemotherapy containing all- trans retinoic acid (ATRA) and idarubicin. On the sixth day of therapy, she developed sinus bradycardia and differentiation syndrome (DS). Electrolytes and cardiac imaging were nor...

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Veröffentlicht in:Journal of family medicine and primary care 2022-07, Vol.11 (7), p.3999-4001
Hauptverfasser: Rathod, Santosh Govind, Khan, Afaq Ahmad, Geelani, Sajad Ahmed, Roshan, Reshma, Bhat, Javid Rasool
Format: Artikel
Sprache:eng
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Case Report
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Zusammenfassung:A 45-year-old female, a new case of acute promyelocytic leukemia (APL), received induction chemotherapy containing all- trans retinoic acid (ATRA) and idarubicin. On the sixth day of therapy, she developed sinus bradycardia and differentiation syndrome (DS). Electrolytes and cardiac imaging were normal. The patient achieved normal sinus rhythm after ATRA was withheld, and DS was treated.
ISSN:2249-4863
2278-7135
DOI:10.4103/jfmpc.jfmpc_1663_21