Plasma D-dimer levels are correlated with disease severity among hypertensive patients: A comparative cross-sectional study

It has been reported that inappropriate acute thrombus formation is the pathophysiological substrate underlying increased risk and severity of target organ damage in hypertension (HTN). However, the relationship between severity of HTN and D-dimer has not been well characterized. The study was aimed...

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Veröffentlicht in:Medicine (Baltimore) 2022-09, Vol.101 (36), p.e30281-e30281
Hauptverfasser: Long, Yanli, Li, Yi, Zhang, Litao, Tao, Liang, Xiao, Hongyan, Li, Ying, Zhou, Chunyou
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Sprache:eng
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Zusammenfassung:It has been reported that inappropriate acute thrombus formation is the pathophysiological substrate underlying increased risk and severity of target organ damage in hypertension (HTN). However, the relationship between severity of HTN and D-dimer has not been well characterized. The study was aimed to assess plasma D-dimer level and its correlation with disease severity among hypertensives. A comparative cross-sectional study was conducted at Wuhan Asia Heart Hospital among 100 participants (60 hypertensives and 40 controls). The correlation between variables were determined using correlation coefficients, regression analysis, and also using different parametric and nonparametric tests. We observed higher D-dimer levels among hypertensives compared to the healthy controls (P 
ISSN:1536-5964
0025-7974
1536-5964
DOI:10.1097/MD.0000000000030281