PhaMMseqs: a new pipeline for constructing phage gene phamilies using MMseqs2

PhaMMseqs: a new pipeline for constructing phage gene phamilies using MMseqs2

The diversity and mosaic architecture of phage genomes present challenges for whole-genome phylogenies and comparative genomics. There are no universally conserved core genes, ∼70% of phage genes are of unknown function, and phage genomes are replete with small (

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Veröffentlicht in:G3 : genes - genomes - genetics 2022-11, Vol.12 (11)
Hauptverfasser: Gauthier, Christian H, Cresawn, Steven G, Hatfull, Graham F
Format: Artikel
Sprache:eng
Schlagworte:
Amino acids
Analysis
Design and construction
Genes
Genomes
Genomics
Phylogeny
Pipelines
Proteins
Software and Data Resources
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Beschreibung
Zusammenfassung:The diversity and mosaic architecture of phage genomes present challenges for whole-genome phylogenies and comparative genomics. There are no universally conserved core genes, ∼70% of phage genes are of unknown function, and phage genomes are replete with small (
ISSN:2160-1836
2160-1836
DOI:10.1093/g3journal/jkac233