Curcumin: A dietary phytochemical for boosting exercise performance and recovery

Curcumin, as the main natural compound in the turmeric plant (Curcuma longa), is a yellowish polyphenol that has been used traditionally in Asian countries as a medicinal herb for various types of disease and pathological conditions caused by inflammation and oxidative stress. In the present review,...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Veröffentlicht in:Food science & nutrition 2022-11, Vol.10 (11), p.3531-3543
Hauptverfasser: Nosrati‐Oskouie, Mohammad, Aghili‐Moghaddam, Nazanin Sadat, Tavakoli‐Rouzbehani, Omid Mohammad, Jamialahmadi, Tannaz, Johnston, Thomas P., Sahebkar, Amirhossein
Format: Artikel
Sprache:eng
Schlagworte:
Online-Zugang:Volltext
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page 3543
container_issue 11
container_start_page 3531
container_title Food science & nutrition
container_volume 10
creator Nosrati‐Oskouie, Mohammad
Aghili‐Moghaddam, Nazanin Sadat
Tavakoli‐Rouzbehani, Omid Mohammad
Jamialahmadi, Tannaz
Johnston, Thomas P.
Sahebkar, Amirhossein
description Curcumin, as the main natural compound in the turmeric plant (Curcuma longa), is a yellowish polyphenol that has been used traditionally in Asian countries as a medicinal herb for various types of disease and pathological conditions caused by inflammation and oxidative stress. In the present review, we conducted a comprehensive literature search for evidence that shows the effect of curcumin on factors influencing exercise performance, including muscle damage, muscle soreness, inflammation, and oxidative stress. During exercise, reactive oxygen species and inflammation are increased. Thus, if there is no balance between endogenous and exogenous antioxidants and increases in oxidative stress and inflammation, which is important for maintaining redox homeostasis in skeletal muscle, it can lead to muscle soreness and muscle damage and ultimately result in reduced exercise performance. Due to the anti‐oxidant and anti‐inflammatory properties of curcumin, it can increase exercise performance and decrease exercise‐induced muscle soreness and muscle damage. It appears that curcumin supplementation can have positive effects on exercise performance and recovery, muscle damage and pain, inflammation, and oxidative stress. However, there is still a need to precisely evaluate factors to more accurately assess/quantify the beneficial therapeutic effects of curcumin with regard to enhancing exercise performance and recovery. Curcumin, by functioning as an antioxidant, may reduce oxidative stress to cells, and especially mitochondria, in the long‐term, as well as positively impact exercise endurance, strength, and recovery to improve overall health.
doi_str_mv 10.1002/fsn3.2983
format Article
fullrecord <record><control><sourceid>proquest_pubme</sourceid><recordid>TN_cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9632206</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2734617548</sourcerecordid><originalsourceid>FETCH-LOGICAL-c3733-78af732d66abbd7d1b5add72a6f6ae112808bd8a17532a8663a57f35d697e2cb3</originalsourceid><addsrcrecordid>eNp1kV1LHTEQhkOpVLFe9A-UgDf14mg-dpOsF4Ic1BbEFtpeh2wy64nsJqfJru3592Y9VqzQ3ExgHp6Z4UXoAyXHlBB20uXAj1mj-Bu0x0ilFpJK-fbFfxcd5HxHymsqKhh7h3a54JVSpNlD35ZTstPgwyk-x87DaNIGr1ebMdoVDN6aHncx4TbGPPpwi-EPJOsz4DWk0hhMsIBNcDiBjfeQNu_RTmf6DAdPdR_9vLz4sfy8uP569WV5fr2wXHK-kMp0kjMnhGlbJx1ta-OcZEZ0wgClTBHVOmWorDkzSghuatnx2olGArMt30dnW-96agdwFsKYTK_XyQ_lBB2N1_92gl_p23ivG8EZI6IIPj0JUvw1QR714LOFvjcB4pQ1k7wSZXylCnr4Cr2LUwrlvJmiXNS0moVHW8qmmHOC7nkZSvQclZ6j0nNUhf34cvtn8m8wBTjZAr99D5v_m_Tl9xv-qHwA3q2eng</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2731365146</pqid></control><display><type>article</type><title>Curcumin: A dietary phytochemical for boosting exercise performance and recovery</title><source>Wiley Online Library Journals Frontfile Complete</source><source>Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals</source><source>Wiley Online Library Open Access</source><source>PubMed Central</source><creator>Nosrati‐Oskouie, Mohammad ; Aghili‐Moghaddam, Nazanin Sadat ; Tavakoli‐Rouzbehani, Omid Mohammad ; Jamialahmadi, Tannaz ; Johnston, Thomas P. ; Sahebkar, Amirhossein</creator><creatorcontrib>Nosrati‐Oskouie, Mohammad ; Aghili‐Moghaddam, Nazanin Sadat ; Tavakoli‐Rouzbehani, Omid Mohammad ; Jamialahmadi, Tannaz ; Johnston, Thomas P. ; Sahebkar, Amirhossein</creatorcontrib><description>Curcumin, as the main natural compound in the turmeric plant (Curcuma longa), is a yellowish polyphenol that has been used traditionally in Asian countries as a medicinal herb for various types of disease and pathological conditions caused by inflammation and oxidative stress. In the present review, we conducted a comprehensive literature search for evidence that shows the effect of curcumin on factors influencing exercise performance, including muscle damage, muscle soreness, inflammation, and oxidative stress. During exercise, reactive oxygen species and inflammation are increased. Thus, if there is no balance between endogenous and exogenous antioxidants and increases in oxidative stress and inflammation, which is important for maintaining redox homeostasis in skeletal muscle, it can lead to muscle soreness and muscle damage and ultimately result in reduced exercise performance. Due to the anti‐oxidant and anti‐inflammatory properties of curcumin, it can increase exercise performance and decrease exercise‐induced muscle soreness and muscle damage. It appears that curcumin supplementation can have positive effects on exercise performance and recovery, muscle damage and pain, inflammation, and oxidative stress. However, there is still a need to precisely evaluate factors to more accurately assess/quantify the beneficial therapeutic effects of curcumin with regard to enhancing exercise performance and recovery. Curcumin, by functioning as an antioxidant, may reduce oxidative stress to cells, and especially mitochondria, in the long‐term, as well as positively impact exercise endurance, strength, and recovery to improve overall health.</description><identifier>ISSN: 2048-7177</identifier><identifier>EISSN: 2048-7177</identifier><identifier>DOI: 10.1002/fsn3.2983</identifier><identifier>PMID: 36348809</identifier><language>eng</language><publisher>United States: John Wiley &amp; Sons, Inc</publisher><subject>Antioxidants ; athletes ; Biomarkers ; Biosynthesis ; Curcumin ; Cytokines ; Damage ; Endurance ; Enzymes ; Exercise ; Free radicals ; Gene expression ; Herbal medicine ; Homeostasis ; Inflammation ; Kinases ; Medicinal plants ; metabolism ; Mitochondrial DNA ; Muscles ; Oxidants ; Oxidative stress ; Oxidizing agents ; Phosphorylation ; Proteins ; Reactive oxygen species ; Recovery ; Review ; Reviews ; Skeletal muscle ; Tumor necrosis factor-TNF</subject><ispartof>Food science &amp; nutrition, 2022-11, Vol.10 (11), p.3531-3543</ispartof><rights>2022 The Authors. published by Wiley Periodicals LLC.</rights><rights>2022 The Authors. Food Science &amp; Nutrition published by Wiley Periodicals LLC.</rights><rights>2022. This work is published under http://creativecommons.org/licenses/by/4.0/ (the “License”). Notwithstanding the ProQuest Terms and Conditions, you may use this content in accordance with the terms of the License.</rights><lds50>peer_reviewed</lds50><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c3733-78af732d66abbd7d1b5add72a6f6ae112808bd8a17532a8663a57f35d697e2cb3</citedby><cites>FETCH-LOGICAL-c3733-78af732d66abbd7d1b5add72a6f6ae112808bd8a17532a8663a57f35d697e2cb3</cites><orcidid>0000-0002-8656-1444</orcidid></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktopdf>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632206/pdf/$$EPDF$$P50$$Gpubmedcentral$$Hfree_for_read</linktopdf><linktohtml>$$Uhttps://www.ncbi.nlm.nih.gov/pmc/articles/PMC9632206/$$EHTML$$P50$$Gpubmedcentral$$Hfree_for_read</linktohtml><link.rule.ids>230,314,723,776,780,881,1411,11542,27903,27904,45553,45554,46030,46454,53769,53771</link.rule.ids><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/36348809$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>Nosrati‐Oskouie, Mohammad</creatorcontrib><creatorcontrib>Aghili‐Moghaddam, Nazanin Sadat</creatorcontrib><creatorcontrib>Tavakoli‐Rouzbehani, Omid Mohammad</creatorcontrib><creatorcontrib>Jamialahmadi, Tannaz</creatorcontrib><creatorcontrib>Johnston, Thomas P.</creatorcontrib><creatorcontrib>Sahebkar, Amirhossein</creatorcontrib><title>Curcumin: A dietary phytochemical for boosting exercise performance and recovery</title><title>Food science &amp; nutrition</title><addtitle>Food Sci Nutr</addtitle><description>Curcumin, as the main natural compound in the turmeric plant (Curcuma longa), is a yellowish polyphenol that has been used traditionally in Asian countries as a medicinal herb for various types of disease and pathological conditions caused by inflammation and oxidative stress. In the present review, we conducted a comprehensive literature search for evidence that shows the effect of curcumin on factors influencing exercise performance, including muscle damage, muscle soreness, inflammation, and oxidative stress. During exercise, reactive oxygen species and inflammation are increased. Thus, if there is no balance between endogenous and exogenous antioxidants and increases in oxidative stress and inflammation, which is important for maintaining redox homeostasis in skeletal muscle, it can lead to muscle soreness and muscle damage and ultimately result in reduced exercise performance. Due to the anti‐oxidant and anti‐inflammatory properties of curcumin, it can increase exercise performance and decrease exercise‐induced muscle soreness and muscle damage. It appears that curcumin supplementation can have positive effects on exercise performance and recovery, muscle damage and pain, inflammation, and oxidative stress. However, there is still a need to precisely evaluate factors to more accurately assess/quantify the beneficial therapeutic effects of curcumin with regard to enhancing exercise performance and recovery. Curcumin, by functioning as an antioxidant, may reduce oxidative stress to cells, and especially mitochondria, in the long‐term, as well as positively impact exercise endurance, strength, and recovery to improve overall health.</description><subject>Antioxidants</subject><subject>athletes</subject><subject>Biomarkers</subject><subject>Biosynthesis</subject><subject>Curcumin</subject><subject>Cytokines</subject><subject>Damage</subject><subject>Endurance</subject><subject>Enzymes</subject><subject>Exercise</subject><subject>Free radicals</subject><subject>Gene expression</subject><subject>Herbal medicine</subject><subject>Homeostasis</subject><subject>Inflammation</subject><subject>Kinases</subject><subject>Medicinal plants</subject><subject>metabolism</subject><subject>Mitochondrial DNA</subject><subject>Muscles</subject><subject>Oxidants</subject><subject>Oxidative stress</subject><subject>Oxidizing agents</subject><subject>Phosphorylation</subject><subject>Proteins</subject><subject>Reactive oxygen species</subject><subject>Recovery</subject><subject>Review</subject><subject>Reviews</subject><subject>Skeletal muscle</subject><subject>Tumor necrosis factor-TNF</subject><issn>2048-7177</issn><issn>2048-7177</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>24P</sourceid><sourceid>WIN</sourceid><sourceid>8G5</sourceid><sourceid>ABUWG</sourceid><sourceid>AFKRA</sourceid><sourceid>AZQEC</sourceid><sourceid>BENPR</sourceid><sourceid>CCPQU</sourceid><sourceid>DWQXO</sourceid><sourceid>GNUQQ</sourceid><sourceid>GUQSH</sourceid><sourceid>M2O</sourceid><recordid>eNp1kV1LHTEQhkOpVLFe9A-UgDf14mg-dpOsF4Ic1BbEFtpeh2wy64nsJqfJru3592Y9VqzQ3ExgHp6Z4UXoAyXHlBB20uXAj1mj-Bu0x0ilFpJK-fbFfxcd5HxHymsqKhh7h3a54JVSpNlD35ZTstPgwyk-x87DaNIGr1ebMdoVDN6aHncx4TbGPPpwi-EPJOsz4DWk0hhMsIBNcDiBjfeQNu_RTmf6DAdPdR_9vLz4sfy8uP569WV5fr2wXHK-kMp0kjMnhGlbJx1ta-OcZEZ0wgClTBHVOmWorDkzSghuatnx2olGArMt30dnW-96agdwFsKYTK_XyQ_lBB2N1_92gl_p23ivG8EZI6IIPj0JUvw1QR714LOFvjcB4pQ1k7wSZXylCnr4Cr2LUwrlvJmiXNS0moVHW8qmmHOC7nkZSvQclZ6j0nNUhf34cvtn8m8wBTjZAr99D5v_m_Tl9xv-qHwA3q2eng</recordid><startdate>202211</startdate><enddate>202211</enddate><creator>Nosrati‐Oskouie, Mohammad</creator><creator>Aghili‐Moghaddam, Nazanin Sadat</creator><creator>Tavakoli‐Rouzbehani, Omid Mohammad</creator><creator>Jamialahmadi, Tannaz</creator><creator>Johnston, Thomas P.</creator><creator>Sahebkar, Amirhossein</creator><general>John Wiley &amp; Sons, Inc</general><general>John Wiley and Sons Inc</general><scope>24P</scope><scope>WIN</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7X2</scope><scope>7X7</scope><scope>7XB</scope><scope>8C1</scope><scope>8FE</scope><scope>8FH</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>8G5</scope><scope>ABUWG</scope><scope>AEUYN</scope><scope>AFKRA</scope><scope>ATCPS</scope><scope>AZQEC</scope><scope>BENPR</scope><scope>BHPHI</scope><scope>CCPQU</scope><scope>DWQXO</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>GNUQQ</scope><scope>GUQSH</scope><scope>HCIFZ</scope><scope>K9.</scope><scope>KB0</scope><scope>M0K</scope><scope>M0S</scope><scope>M2O</scope><scope>MBDVC</scope><scope>NAPCQ</scope><scope>PIMPY</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope><scope>PRINS</scope><scope>Q9U</scope><scope>7X8</scope><scope>5PM</scope><orcidid>https://orcid.org/0000-0002-8656-1444</orcidid></search><sort><creationdate>202211</creationdate><title>Curcumin: A dietary phytochemical for boosting exercise performance and recovery</title><author>Nosrati‐Oskouie, Mohammad ; Aghili‐Moghaddam, Nazanin Sadat ; Tavakoli‐Rouzbehani, Omid Mohammad ; Jamialahmadi, Tannaz ; Johnston, Thomas P. ; Sahebkar, Amirhossein</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c3733-78af732d66abbd7d1b5add72a6f6ae112808bd8a17532a8663a57f35d697e2cb3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2022</creationdate><topic>Antioxidants</topic><topic>athletes</topic><topic>Biomarkers</topic><topic>Biosynthesis</topic><topic>Curcumin</topic><topic>Cytokines</topic><topic>Damage</topic><topic>Endurance</topic><topic>Enzymes</topic><topic>Exercise</topic><topic>Free radicals</topic><topic>Gene expression</topic><topic>Herbal medicine</topic><topic>Homeostasis</topic><topic>Inflammation</topic><topic>Kinases</topic><topic>Medicinal plants</topic><topic>metabolism</topic><topic>Mitochondrial DNA</topic><topic>Muscles</topic><topic>Oxidants</topic><topic>Oxidative stress</topic><topic>Oxidizing agents</topic><topic>Phosphorylation</topic><topic>Proteins</topic><topic>Reactive oxygen species</topic><topic>Recovery</topic><topic>Review</topic><topic>Reviews</topic><topic>Skeletal muscle</topic><topic>Tumor necrosis factor-TNF</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Nosrati‐Oskouie, Mohammad</creatorcontrib><creatorcontrib>Aghili‐Moghaddam, Nazanin Sadat</creatorcontrib><creatorcontrib>Tavakoli‐Rouzbehani, Omid Mohammad</creatorcontrib><creatorcontrib>Jamialahmadi, Tannaz</creatorcontrib><creatorcontrib>Johnston, Thomas P.</creatorcontrib><creatorcontrib>Sahebkar, Amirhossein</creatorcontrib><collection>Wiley Online Library Open Access</collection><collection>Wiley Free Content</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Agricultural Science Collection</collection><collection>Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Public Health Database</collection><collection>ProQuest SciTech Collection</collection><collection>ProQuest Natural Science Collection</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>Research Library (Alumni Edition)</collection><collection>ProQuest Central (Alumni Edition)</collection><collection>ProQuest One Sustainability</collection><collection>ProQuest Central UK/Ireland</collection><collection>Agricultural &amp; Environmental Science Collection</collection><collection>ProQuest Central Essentials</collection><collection>ProQuest Central</collection><collection>Natural Science Collection</collection><collection>ProQuest One Community College</collection><collection>ProQuest Central Korea</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>ProQuest Central Student</collection><collection>Research Library Prep</collection><collection>SciTech Premium Collection</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Agricultural Science Database</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Research Library</collection><collection>Research Library (Corporate)</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Publicly Available Content Database</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><collection>ProQuest Central China</collection><collection>ProQuest Central Basic</collection><collection>MEDLINE - Academic</collection><collection>PubMed Central (Full Participant titles)</collection><jtitle>Food science &amp; nutrition</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Nosrati‐Oskouie, Mohammad</au><au>Aghili‐Moghaddam, Nazanin Sadat</au><au>Tavakoli‐Rouzbehani, Omid Mohammad</au><au>Jamialahmadi, Tannaz</au><au>Johnston, Thomas P.</au><au>Sahebkar, Amirhossein</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Curcumin: A dietary phytochemical for boosting exercise performance and recovery</atitle><jtitle>Food science &amp; nutrition</jtitle><addtitle>Food Sci Nutr</addtitle><date>2022-11</date><risdate>2022</risdate><volume>10</volume><issue>11</issue><spage>3531</spage><epage>3543</epage><pages>3531-3543</pages><issn>2048-7177</issn><eissn>2048-7177</eissn><abstract>Curcumin, as the main natural compound in the turmeric plant (Curcuma longa), is a yellowish polyphenol that has been used traditionally in Asian countries as a medicinal herb for various types of disease and pathological conditions caused by inflammation and oxidative stress. In the present review, we conducted a comprehensive literature search for evidence that shows the effect of curcumin on factors influencing exercise performance, including muscle damage, muscle soreness, inflammation, and oxidative stress. During exercise, reactive oxygen species and inflammation are increased. Thus, if there is no balance between endogenous and exogenous antioxidants and increases in oxidative stress and inflammation, which is important for maintaining redox homeostasis in skeletal muscle, it can lead to muscle soreness and muscle damage and ultimately result in reduced exercise performance. Due to the anti‐oxidant and anti‐inflammatory properties of curcumin, it can increase exercise performance and decrease exercise‐induced muscle soreness and muscle damage. It appears that curcumin supplementation can have positive effects on exercise performance and recovery, muscle damage and pain, inflammation, and oxidative stress. However, there is still a need to precisely evaluate factors to more accurately assess/quantify the beneficial therapeutic effects of curcumin with regard to enhancing exercise performance and recovery. Curcumin, by functioning as an antioxidant, may reduce oxidative stress to cells, and especially mitochondria, in the long‐term, as well as positively impact exercise endurance, strength, and recovery to improve overall health.</abstract><cop>United States</cop><pub>John Wiley &amp; Sons, Inc</pub><pmid>36348809</pmid><doi>10.1002/fsn3.2983</doi><tpages>13</tpages><orcidid>https://orcid.org/0000-0002-8656-1444</orcidid><oa>free_for_read</oa></addata></record>
fulltext fulltext
identifier ISSN: 2048-7177
ispartof Food science & nutrition, 2022-11, Vol.10 (11), p.3531-3543
issn 2048-7177
2048-7177
language eng
recordid cdi_pubmedcentral_primary_oai_pubmedcentral_nih_gov_9632206
source Wiley Online Library Journals Frontfile Complete; Elektronische Zeitschriftenbibliothek - Frei zugängliche E-Journals; Wiley Online Library Open Access; PubMed Central
subjects Antioxidants
athletes
Biomarkers
Biosynthesis
Curcumin
Cytokines
Damage
Endurance
Enzymes
Exercise
Free radicals
Gene expression
Herbal medicine
Homeostasis
Inflammation
Kinases
Medicinal plants
metabolism
Mitochondrial DNA
Muscles
Oxidants
Oxidative stress
Oxidizing agents
Phosphorylation
Proteins
Reactive oxygen species
Recovery
Review
Reviews
Skeletal muscle
Tumor necrosis factor-TNF
title Curcumin: A dietary phytochemical for boosting exercise performance and recovery
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-01-24T00%3A08%3A02IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_pubme&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Curcumin:%20A%20dietary%20phytochemical%20for%20boosting%20exercise%20performance%20and%20recovery&rft.jtitle=Food%20science%20&%20nutrition&rft.au=Nosrati%E2%80%90Oskouie,%20Mohammad&rft.date=2022-11&rft.volume=10&rft.issue=11&rft.spage=3531&rft.epage=3543&rft.pages=3531-3543&rft.issn=2048-7177&rft.eissn=2048-7177&rft_id=info:doi/10.1002/fsn3.2983&rft_dat=%3Cproquest_pubme%3E2734617548%3C/proquest_pubme%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_pqid=2731365146&rft_id=info:pmid/36348809&rfr_iscdi=true