Nontargeted and Targeted Metabolomic Profiling Reveals Novel Metabolite Biomarkers of Incident Diabetes in African Americans

Nontargeted metabolomics methods have increased potential to identify new disease biomarkers, but assessments of the additive information provided in large human cohorts by these less biased techniques are limited. To diversify our knowledge of diabetes-associated metabolites, we leveraged a method...

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Veröffentlicht in:	Diabetes (New York, N.Y.) N.Y.), 2022-11, Vol.71 (11), p.2426-2437
Hauptverfasser:	Chen, Zsu-Zsu, Pacheco, Julian Avila, Gao, Yan, Deng, Shuliang, Peterson, Bennet, Shi, Xu, Zheng, Shuning, Tahir, Usman A, Katz, Daniel H, Cruz, Daniel E, Ngo, Debby, Benson, Mark D, Robbins, Jeremy M, Guo, Xiuqing, Del Rocio Sevilla Gonzalez, Magdalena, Manning, Alisa, Correa, Adolfo, Meigs, James B, Taylor, Kent D, Rich, Stephen S, Goodarzi, Mark O, Rotter, Jerome I, Wilson, James G, Clish, Clary B, Gerszten, Robert E
Format:	Artikel
Sprache:	eng
Schlagworte:	African Americans Biomarkers Black or African American Blood Glucose - metabolism Diabetes Diabetes Mellitus Fasting Genetics/Genomes/Proteomics/Metabolomics Humans Mass spectroscopy Metabolites Metabolomics Metabolomics - methods Risk factors
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