The CAIDE Dementia Risk Score and the Honolulu-Asia Aging Study

Introduction: The CAIDE (Cardiovascular Risk Factors, Aging, and Incidence of Dementia) dementia risk score is based on demographic, genetic, and modifiable risk factors in midlife and has been shown to be predictive of later-life dementia. Objective: To test the predictive capacity of the CAIDE dem...

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Veröffentlicht in:Dementia and geriatric cognitive disorders 2019-01, Vol.48 (3-4), p.164-171
Hauptverfasser: Chosy, E. Julia, Edland, Steven D., Gross, Noele, Meyer, Marnie J., Liu, Catherine Y., Launer, Lenore J., White, Lon R.
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Sprache:eng
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Zusammenfassung:Introduction: The CAIDE (Cardiovascular Risk Factors, Aging, and Incidence of Dementia) dementia risk score is based on demographic, genetic, and modifiable risk factors in midlife and has been shown to be predictive of later-life dementia. Objective: To test the predictive capacity of the CAIDE dementia risk score among a cohort of Japanese-American men. Methods: Midlife measures were obtained from a sample of 3,582 Japanese-American men in the Honolulu Heart Program (1965–1968, average age = 53.1 years). A follow-up exam in 1991 (average age = 77.8 years) assessed cognitive impairment using the Cognitive Abilities Screening Instrument (CASI). Severe cognitive impairment was defined as a CASI score
ISSN:1420-8008
1421-9824
DOI:10.1159/000504801