Host Biomarkers Reflect Prognosis in Patients Presenting With Moderate Coronavirus Disease 2019: A Prospective Cohort Study

Host Biomarkers Reflect Prognosis in Patients Presenting With Moderate Coronavirus Disease 2019: A Prospective Cohort Study

Efficient resource allocation is essential for effective pandemic response. We measured host biomarkers in 420 patients presenting with moderate coronavirus disease 2019 and found that different biomarkers predict distinct clinical outcomes. Interleukin (IL)-1ra, IL-6, IL-10, and IL-8 exhibit dose-r...

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Veröffentlicht in:Open Forum Infectious Diseases 2022-10, Vol.9 (10), p.ofac526-ofac526
Hauptverfasser: Chandna, Arjun, Mahajan, Raman, Gautam, Priyanka, Mwandigha, Lazaro, Kumar, Pragya, Varghese, George M, Koshiaris, Constantinos, Lubell, Yoel, Burza, Sakib
Format: Artikel
Sprache:eng
Schlagworte:
Biological markers
Brief Report
Coronaviruses
Development and progression
Ethylenediaminetetraacetic acid
Infection
Interleukins
Medical research
Medicine, Experimental
Rationing
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Zusammenfassung:Efficient resource allocation is essential for effective pandemic response. We measured host biomarkers in 420 patients presenting with moderate coronavirus disease 2019 and found that different biomarkers predict distinct clinical outcomes. Interleukin (IL)-1ra, IL-6, IL-10, and IL-8 exhibit dose-response relationships with subsequent disease progression and could potentially be useful for multiple use-cases.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofac526