Neurodegenerative Diseases: Implications of Environmental and Climatic Influences on Neurotransmitters and Neuronal Hormones Activities

Neurodegenerative and neuronal-related diseases are major public health concerns. Human vulnerability to neurodegenerative diseases (NDDs) increases with age. Neuronal hormones and neurotransmitters are major determinant factors regulating brain structure and functions. The implications of environme...

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Veröffentlicht in:International journal of environmental research and public health 2022-09, Vol.19 (19), p.12495
Hauptverfasser: Ayeni, Emmanuel A, Aldossary, Ahmad M, Ayejoto, Daniel A, Gbadegesin, Lanre A, Alshehri, Abdullah A, Alfassam, Haya A, Afewerky, Henok K, Almughem, Fahad A, Bello, Saidu M, Tawfik, Essam A
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Sprache:eng
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Zusammenfassung:Neurodegenerative and neuronal-related diseases are major public health concerns. Human vulnerability to neurodegenerative diseases (NDDs) increases with age. Neuronal hormones and neurotransmitters are major determinant factors regulating brain structure and functions. The implications of environmental and climatic changes emerged recently as influence factors on numerous diseases. However, the complex interaction of neurotransmitters and neuronal hormones and their depletion under environmental and climatic influences on NDDs are not well established in the literature. In this review, we aim to explore the connection between the environmental and climatic factors to NDDs and to highlight the available and potential therapeutic interventions that could use to improve the quality of life and reduce susceptibility to NDDs.
ISSN:1660-4601
1661-7827
1660-4601
DOI:10.3390/ijerph191912495