Change in functional status associated with respiratory syncytial virus infection in hospitalized older adults

Background Respiratory syncytial virus (RSV) causes severe respiratory illnesses in infants and older adults. Older adults are frequently hospitalized with RSV illness and may experience loss of function. This study evaluated longitudinal changes in function associated with RSV hospitalization in ol...

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Veröffentlicht in:Influenza and other respiratory viruses 2022-11, Vol.16 (6), p.1151-1160
Hauptverfasser: Branche, Angela R., Saiman, Lisa, Walsh, Edward E., Falsey, Ann R., Jia, Haomiao, Barrett, Angela, Alba, Luis, Phillips, Matthew, Finelli, Lyn
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Sprache:eng
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Zusammenfassung:Background Respiratory syncytial virus (RSV) causes severe respiratory illnesses in infants and older adults. Older adults are frequently hospitalized with RSV illness and may experience loss of function. This study evaluated longitudinal changes in function associated with RSV hospitalization in older adults. Methods Adults ≥60 years hospitalized with laboratory‐confirmed RSV were enrolled (N = 302). Demographics and comorbidities were collected. Functional status was assessed 2 weeks pre‐hospitalization by recall, at enrollment, hospital discharge and 2, 4, and 6 months post‐discharge using the Lawton–Brody Instrumental Activities of Daily Living (IADL) (scale 0–8) and Barthel ADL Index (scale 0–100). Results RSV‐associated hospitalization resulted in acute functional loss. Median IADL (5 vs. 3, p 
ISSN:1750-2640
1750-2659
DOI:10.1111/irv.13043