The efficacy of mindfulness-based intervention for heart diseases: A meta-analysis of randomized controlled trials

The efficacy of mindfulness-based intervention for heart diseases remains controversial. We conduct a systematic review and meta-analysis to explore the impact of mindfulness-based intervention on heart diseases. We have search PubMed, EMbase, Web of science, EBSCO, and Cochrane library databases through August 2020 for randomized controlled trials (RCTs) assessing the effect of mindfulness-based intervention versus usual care on heart diseases. This meta-analysis is performed using the random-effect model. Five RCTs involving 458 patients are included in the meta-analysis. Overall, compared with control group for heart diseases, mindfulness-based intervention is associated with significantly increased 6 minute walking test [mean difference (MD) = 14.74; 95% confidence interval (95% CI) = 2.50-26.97; P = .02], decreased heart rate (MD = -2.54; 95% CI = -4.76 to -0.31; P = .03) and stress score (MD = -2.31; 95% CI = -4.23 to -0.38; P = .02), but shows no obvious impact on anxiety score (MD = -3.48; 95% CI = -7.98 to 1.03; P = .13) or respiratory rate (MD = -0.42; 95% CI = -1.31 to 0.46; P = .35). Mindfulness-based intervention can provide additional benefits to heart diseases.