Time to Culture Conversion of Bedaquiline and High-Dose Isoniazid for Drug-Resistant Tuberculosis

Abstract Patients with multidrug-resistant tuberculosis who received regimens containing high-dose isoniazid (INHHD) had similar time to culture conversion and treatment outcomes as patients who received regimens with bedaquiline. INHHD is an inexpensive and safe medication that may contribute addit...

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Veröffentlicht in:	Open Forum Infectious Diseases 2022-09, Vol.9 (9), p.ofac440
Hauptverfasser:	Walsh, Kathleen F, Vilbrun, Stalz Charles, Souroutzidis, Ariadne, Ellis, Joshua, Delva, Sobiesyke, Joissaint, Guy, Dupnik, Kathryn M, Joseph, Patrice, Pape, Jean W, Koenig, Serena P
Format:	Artikel
Sprache:	eng
Schlagworte:	Antitubercular agents Brief Report Dosage and administration Drug resistance in microorganisms Drug therapy Drugs Health aspects Tuberculosis
Online-Zugang:	Volltext
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Zusammenfassung:	Abstract Patients with multidrug-resistant tuberculosis who received regimens containing high-dose isoniazid (INHHD) had similar time to culture conversion and treatment outcomes as patients who received regimens with bedaquiline. INHHD is an inexpensive and safe medication that may contribute additive efficacy in combination regimens.
ISSN:	2328-8957 2328-8957
DOI:	10.1093/ofid/ofac440