Effects of Vaccination and Previous Infection on Omicron Infections in Children

In a 6-month study in children while omicron was dominant, previous SARS-CoV-2 infection and the BNT162b2 vaccine lowered the risks of infection, hospitalization, and death, but protection against omicron declined rapidly.

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Bibliographische Detailangaben
Veröffentlicht in:	The New England journal of medicine 2022-09, Vol.387 (12), p.1141-1143
Hauptverfasser:	Lin, Dan-Yu, Gu, Yu, Xu, Yangjianchen, Zeng, Donglin, Wheeler, Bradford, Young, Hayley, Sunny, Shadia Khan, Moore, Zack
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Child Children Coronavirus Coronaviruses Correspondence COVID-19 - genetics COVID-19 - immunology COVID-19 - prevention & control COVID-19 - virology COVID-19 vaccines COVID-19 Vaccines - immunology COVID-19 Vaccines - therapeutic use Disease transmission FDA approval Hospitalization Humans Immunization Infections Infectious Disease Pediatrics Pediatrics General Reinfection - genetics Reinfection - immunology Reinfection - prevention & control Reinfection - virology SARS-CoV-2 - genetics SARS-CoV-2 - immunology Severe acute respiratory syndrome coronavirus 2 Vaccination Vaccines
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Beschreibung
Zusammenfassung:	In a 6-month study in children while omicron was dominant, previous SARS-CoV-2 infection and the BNT162b2 vaccine lowered the risks of infection, hospitalization, and death, but protection against omicron declined rapidly.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMc2209371