Neutralization of SARS-CoV-2 Omicron BA.2.75 after mRNA-1273 Vaccination

Neutralization of SARS-CoV-2 Omicron BA.2.75 after mRNA-1273 Vaccination

A booster dose of mRNA-1273 after the initial two-dose vaccination resulted in neutralization titers against the BA.2.75 variant that were similar to those against BA.1 and BA.2 and higher than those against BA.5.

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Veröffentlicht in:The New England journal of medicine 2022-09, Vol.387 (13), p.1234-1236
Hauptverfasser: Shen, Xiaoying, Chalkias, Spyros, Feng, Jing, Chen, Xing, Zhou, Honghong, Marshall, Jean-Claude, Girard, Bethany, Tomassini, Joanne E., Aunins, Anne, Das, Rituparna, Montefiori, David C.
Format: Artikel
Sprache:eng
Schlagworte:
Antibodies
Confidence intervals
Coronavirus
Coronaviruses
Correspondence
Immunization
Infectious Disease
Medical research
mRNA
Mutation
Severe acute respiratory syndrome coronavirus 2
Vaccination
Vaccines
Viral Infections
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Beschreibung
Zusammenfassung:A booster dose of mRNA-1273 after the initial two-dose vaccination resulted in neutralization titers against the BA.2.75 variant that were similar to those against BA.1 and BA.2 and higher than those against BA.5.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMc2210648