Learn to Estimate Genetic Mutation and Microsatellite Instability with Histopathology H&E Slides in Colon Carcinoma

Colorectal cancer is one of the most common malignancies and the third leading cause of cancer-related mortality worldwide. Identifying KRAS, NRAS, and BRAF mutations and estimating MSI status is closely related to the individualized therapeutic judgment and oncologic prognosis of CRC patients. In t...

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Veröffentlicht in:	Cancers 2022-08, Vol.14 (17), p.4144
Hauptverfasser:	Guo, Yimin, Lyu, Ting, Liu, Shuguang, Zhang, Wei, Zhou, Youjian, Zeng, Chao, Wu, Guangming
Format:	Artikel
Sprache:	eng
Schlagworte:	Artificial intelligence Cancer Carcinoma Classification Colon cancer Colorectal cancer Colorectal carcinoma Datasets Fidelity Gene mutations Genetic aspects Health aspects Histology, Pathological Medical prognosis Metastasis Microsatellite instability Microsatellites (Genetics) Mortality Mutation Neural networks Oncology, Experimental Patients Point mutation Predictions Prognosis Tumors
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