Antiretroviral therapy initiation within 7 and 8–30 days post-HIV diagnosis demonstrates similar benefits in resource-limited settings
We estimated the optimum time to initiate antiretroviral therapy (ART) in a retrospective observational cohort. We observed that ART initiation 7 days or less ( n = 817) and 8–30 days ( n = 1009) were the most important factors with viral suppression, and had similar viral suppression rate, CD4 +...
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Veröffentlicht in: | AIDS (London) 2022-10, Vol.36 (12), p.1741-1743 |
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Hauptverfasser: | , , , , , , , , , , , , , |
Format: | Artikel |
Sprache: | eng |
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Zusammenfassung: | We estimated the optimum time to initiate antiretroviral therapy (ART) in a retrospective observational cohort. We observed that ART initiation 7 days or less (
n
= 817) and 8–30 days (
n
= 1009) were the most important factors with viral suppression, and had similar viral suppression rate, CD4
+
T-cell count increase and fractions of individuals with links at least 4 and individuals linked to recent HIV infection in HIV molecular networks. This study provides real-world evidence on the benefits of rapid ART initiation in resource-limited setting. |
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ISSN: | 0269-9370 1473-5571 |
DOI: | 10.1097/QAD.0000000000003327 |