A Case of Colon Cancer and Pauci-Immune Crescentic Glomerulonephritis

A Case of Colon Cancer and Pauci-Immune Crescentic Glomerulonephritis

The association between membranous nephropathy and cancer has been well documented. Crescentic glomerulonephritis (GN) has also been associated with various types of cancers. To our knowledge, there has only been one previously documented case of seronegative pauci-immune crescentic glomerulonephrit...

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Veröffentlicht in:Curēus (Palo Alto, CA) CA), 2022-07, Vol.14 (7)
Hauptverfasser: Wilhelm, David, Caster, Dawn, Coventry, Susan, Garg, Gunjan
Format: Artikel
Sprache:eng
Schlagworte:
Abdomen
Antibodies
Antigens
Biopsy
Cancer therapies
Case reports
Chemotherapy
Colorectal cancer
Creatinine
Disease
Hematuria
Hemodialysis
Hospitals
Immunoglobulins
Immunotherapy
Kidneys
Metastasis
Microscopy
Monoclonal antibodies
Nephrology
Neutrophils
Oncology
Patients
Targeted cancer therapy
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Zusammenfassung:The association between membranous nephropathy and cancer has been well documented. Crescentic glomerulonephritis (GN) has also been associated with various types of cancers. To our knowledge, there has only been one previously documented case of seronegative pauci-immune crescentic glomerulonephritis associated with colon cancer. We present a case of a 51-year-old male with newly diagnosed high-grade poorly-differentiated colon carcinoma who was found to have seronegative pauci-immune crescentic GN with 70% involvement of glomeruli on renal biopsy. The patient was treated with pulse steroids and rituximab with resolution of acute kidney injury.
ISSN:2168-8184
2168-8184
DOI:10.7759/cureus.27460