Serum 25-Hydroxyvitamin D is Associated With Bone Microarchitecture and Strength in a Multiracial Cohort of Young Adults

To determine whether 25-hydroxyvitamin D (25-OH D) levels are associated with bone outcomes in a multiracial cohort of young adults. This cross-sectional study included 165 participants (83 men, 82 women, 18-30 years of age) who self-identified as Asian, Black, or White. We measured bone microarchit...

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Veröffentlicht in:	The journal of clinical endocrinology and metabolism 2022-09, Vol.107 (9), p.e3679-e3688
Hauptverfasser:	Garrahan, Margaret, Gehman, Sarah, Rudolph, Sara E, Tenforde, Adam S, Ackerman, Kathryn E, Popp, Kristin L, Bouxsein, Mary L, Sahni, Shivani
Format:	Artikel
Sprache:	eng
Schlagworte:	Absorptiometry, Photon Alfacalcidol Analysis Bone and Bones - diagnostic imaging Bone Density Bones Calcifediol Cross-Sectional Studies CT imaging Density Exercise Female Food habits Humans Male Online Only Physical fitness Porosity Racially mixed people Radius - diagnostic imaging Teenagers Tibia - diagnostic imaging Vitamin D Vitamin D - analogs & derivatives Young Adult Youth
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Zusammenfassung:	To determine whether 25-hydroxyvitamin D (25-OH D) levels are associated with bone outcomes in a multiracial cohort of young adults. This cross-sectional study included 165 participants (83 men, 82 women, 18-30 years of age) who self-identified as Asian, Black, or White. We measured bone microarchitecture and strength of the distal radius and tibia using high-resolution peripheral quantitative computed tomography. We used linear regression to estimate the association between 25-OH D (ng/mL) and bone measurements, adjusting for race, sex, age, weight, height, calcium intake, physical activity, and season. A total of 43.6% of participants were 25-OH D deficient (
ISSN:	0021-972X 1945-7197
DOI:	10.1210/clinem/dgac388