Tecovirimat for the Treatment of Human Monkeypox: An Initial Series From Massachusetts, United States

Tecovirimat for the Treatment of Human Monkeypox: An Initial Series From Massachusetts, United States

Abstract A large, ongoing multicountry outbreak of human monkeypox has the potential to cause considerable morbidity and mortality. Therapeutics for the treatment of smallpox, a related Orthopoxvirus, may be used and affect the natural history of monkeypox. We present 3 patients from our hospitals t...

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Veröffentlicht in:Open Forum Infectious Diseases 2022-08, Vol.9 (8), p.ofac377-ofac377
Hauptverfasser: Matias, Wilfredo R, Koshy, Jacob M, Nagami, Ellen H, Kovac, Victor, Moeng, Letumile R, Shenoy, Erica S, Hooper, David C, Madoff, Lawrence C, Barshak, Miriam B, Johnson, Jennifer A, Rowley, Christopher F, Julg, Boris, Hohmann, Elizabeth L, Lazarus, Jacob E
Format: Artikel
Sprache:eng
Schlagworte:
Brief Report
Care and treatment
Health aspects
Hospitals
Human monkeypox
Massachusetts
Smallpox vaccine
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Zusammenfassung:Abstract A large, ongoing multicountry outbreak of human monkeypox has the potential to cause considerable morbidity and mortality. Therapeutics for the treatment of smallpox, a related Orthopoxvirus, may be used and affect the natural history of monkeypox. We present 3 patients from our hospitals treated with tecovirimat, a pan-Orthopoxvirus inhibitor currently available under an expanded access investigational new drug protocol for monkeypox.
ISSN:2328-8957
2328-8957
DOI:10.1093/ofid/ofac377