Comparison of long‐term outcome of patients with ST‐segment elevation myocardial infarction between pre‐COVID‐19 and COVID‐19 era

Aims To compare major cardiovascular and cerebrovascular events (MACCE) rates between patients in the pre‐COVID‐19 era and COVID‐19 era, and to assess the impact of the presence of COVID‐19 (+) on long‐term MACCE in ST‐segment elevation myocardial infarction (STEMI) in Turkey. Methods Using the TURSER study (TURKISH ST‐segment elevation myocardial infarction registry) data, the current study included 1748 STEMI patients from 15 centres in Turkey. Patients were stratified into COVID‐19 era (March 11st–May 15st, 2020; n = 723) or pre‐COVID‐19 era (March 11st–May 15st, 2019; n = 1025) cohorts. Long‐term MACCE rates were compared between groups. In addition, the effect of COVID‐19 positivity on long‐term outcomes was evaluated. The primary outcome was the occurrence of MACCE at long‐term follow‐up, and the secondary outcome was hospitalization with heart failure. Results The MACCE and hospitalization with heart failure rates between pre‐COVID‐19 era and COVID‐19 era were 23% versus 22% (p = .841), and 12% versus 8% (p = .002), respectively. In the COVID‐19 era, the rates of MACCE and hospitalization with heart failure COVID‐19‐positive versus COVID‐19‐negative patients were 40% versus 20%, (p