Associations of facility-level antibiotic use and hospital-onset Clostridioides difficile infection in US acute-care hospitals, 2012–2018

Associations of facility-level antibiotic use and hospital-onset Clostridioides difficile infection in US acute-care hospitals, 2012–2018

Previously reported associations between hospital-level antibiotic use and hospital-onset Clostridioides difficile infection (HO-CDI) were reexamined using 2012–2018 data from a new cohort of US acute-care hospitals. This analysis revealed significant positive associations between total, third-gener...

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Veröffentlicht in:Infection control and hospital epidemiology 2022-08, Vol.43 (8), p.1067-1069
Hauptverfasser: Kazakova, Sophia V., Baggs, James, Yi, Sarah H., Reddy, Sujan C., Hatfield, Kelly M., Guh, Alice Y., Jernigan, John A., McDonald, L. Clifford
Format: Artikel
Sprache:eng
Schlagworte:
Antibiotics
Comorbidity
Concise Communication
Hospitals
Infections
Patients
Trends
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Zusammenfassung:Previously reported associations between hospital-level antibiotic use and hospital-onset Clostridioides difficile infection (HO-CDI) were reexamined using 2012–2018 data from a new cohort of US acute-care hospitals. This analysis revealed significant positive associations between total, third-generation, and fourth-generation cephalosporin, fluoroquinolone, carbapenem, and piperacillin-tazobactam use and HO-CDI rates, confirming previous findings.
ISSN:0899-823X
1559-6834
DOI:10.1017/ice.2021.151