Maternal Vaccination and Risk of Hospitalization for Covid-19 among Infants

In this study, maternal vaccination with an mRNA vaccine during pregnancy was less common among infants hospitalized for Covid-19 than among controls. The effectiveness of maternal vaccination against Covid-19 hospitalization of infants was 52% overall and was greater when delta, rather than omicron...

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Veröffentlicht in:	The New England journal of medicine 2022-07, Vol.387 (2), p.109-119
Hauptverfasser:	Halasa, Natasha B., Olson, Samantha M., Staat, Mary A., Newhams, Margaret M., Price, Ashley M., Pannaraj, Pia S., Boom, Julie A., Sahni, Leila C., Chiotos, Kathleen, Cameron, Melissa A., Bline, Katherine E., Hobbs, Charlotte V., Maddux, Aline B., Coates, Bria M., Michelson, Kelly N., Heidemann, Sabrina M., Irby, Katherine, Nofziger, Ryan A., Mack, Elizabeth H., Smallcomb, Laura, Schwartz, Stephanie P., Walker, Tracie C., Gertz, Shira J., Schuster, Jennifer E., Kamidani, Satoshi, Tarquinio, Keiko M., Bhumbra, Samina S., Maamari, Mia, Hume, Janet R., Crandall, Hillary, Levy, Emily R., Zinter, Matt S., Bradford, Tamara T., Flori, Heidi R., Cullimore, Melissa L., Kong, Michele, Cvijanovich, Natalie Z., Gilboa, Suzanne M., Polen, Kara N., Campbell, Angela P., Randolph, Adrienne G., Patel, Manish M.
Format:	Artikel
Sprache:	eng
Schlagworte:	Age Antibodies Antigens Babies Complications of Pregnancy Coronavirus Coronaviruses COVID-19 COVID-19 - epidemiology COVID-19 - prevention & control COVID-19 vaccines COVID-19 Vaccines - adverse effects COVID-19 Vaccines - therapeutic use Electronic health records Female Gynecology Gynecology General Hospitalization Hospitalization - statistics & numerical data Hospitals Humans Illnesses Immunization Infant Infants Infections Infectious Disease Mechanical ventilation Medical records Mothers mRNA mRNA vaccines mRNA Vaccines - adverse effects mRNA Vaccines - therapeutic use Neonatology Obstetrics Original Pediatrics Pediatrics General Pregnancy Pregnancy Complications, Infectious - epidemiology Pregnancy Complications, Infectious - prevention & control SARS-CoV-2 Severe acute respiratory syndrome coronavirus 2 Surveillance Vaccination Vaccination - statistics & numerical data Vaccine efficacy Vaccines Vaccines, Synthetic Vasoactive agents Ventilators
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Beschreibung
Zusammenfassung:	In this study, maternal vaccination with an mRNA vaccine during pregnancy was less common among infants hospitalized for Covid-19 than among controls. The effectiveness of maternal vaccination against Covid-19 hospitalization of infants was 52% overall and was greater when delta, rather than omicron, was predominant.
ISSN:	0028-4793 1533-4406
DOI:	10.1056/NEJMoa2204399