Assessment of post‐partum haemorrhage risk among women with moderate thrombocytopenia

Summary It is unknown whether moderate thrombocytopenia represents a risk factor for post‐partum haemorrhage (PPH). We assessed PPH risk among women with a platelet count of between 100 and 50 × 109/l and stratified the risk for O/non‐O blood group. We included consecutive women undergoing vaginal d...

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Veröffentlicht in:British journal of haematology 2022-05, Vol.197 (4), p.482-488
Hauptverfasser: Arcudi, Sara, Ronchi, Alice, Capecchi, Marco, Iurlaro, Enrico, Ossola, Manuela W., Mancini, Ilaria, Schivardi, Gabriella, Marconi, Anna Maria, Podda, Gian Marco, Artoni, Andrea
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Sprache:eng
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Zusammenfassung:Summary It is unknown whether moderate thrombocytopenia represents a risk factor for post‐partum haemorrhage (PPH). We assessed PPH risk among women with a platelet count of between 100 and 50 × 109/l and stratified the risk for O/non‐O blood group. We included consecutive women undergoing vaginal delivery or caesarean section with moderate thrombocytopenia. Women with >150 × 109/l platelets at delivery were selected as controls and matched for age, type of birth and ethnicity. Odds ratios (ORs) with their 95% confidence intervals (95% CIs) were calculated as risk estimates. A total of 94 thrombocytopenic women and 94 controls were included in the study. The rate of PPH was significantly higher in thrombocytopenic women than in controls (37% vs. 10%, p 
ISSN:0007-1048
1365-2141
1365-2141
DOI:10.1111/bjh.18098