Omega-3 fatty acid supplementation and fecundability

Abstract STUDY QUESTION Is self-reported use of omega-3 fatty acid supplements associated with fecundability, the probability of natural conception, in a given menstrual cycle? SUMMARY ANSWER Prospectively recorded omega-3 supplement use was associated with an increased probability of conceiving. WH...

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Veröffentlicht in:	Human reproduction (Oxford) 2022-05, Vol.37 (5), p.1037-1046
Hauptverfasser:	Stanhiser, J, Jukic, A M Z, McConnaughey, D R, Steiner, A Z
Format:	Artikel
Sprache:	eng
Schlagworte:	Cohort Studies Dietary Supplements Fatty Acids, Omega-3 Female Fertility Humans Infertility, Female - therapy Original Pregnancy Prospective Studies Time-to-Pregnancy Vitamin D
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Zusammenfassung:	Abstract STUDY QUESTION Is self-reported use of omega-3 fatty acid supplements associated with fecundability, the probability of natural conception, in a given menstrual cycle? SUMMARY ANSWER Prospectively recorded omega-3 supplement use was associated with an increased probability of conceiving. WHAT IS KNOWN ALREADY In infertile women, omega-3 fatty acid intake has been associated with increased probability of pregnancy following IVF. In natural fertility, studies are conflicting, and no study of natural fertility has evaluated omega-3 fatty acid supplementation and fecundity. STUDY DESIGN, SIZE, DURATION Secondary data analysis of 900 women contributing 2510 cycles in Time to Conceive (TTC), a prospective, time to pregnancy cohort study from 2008 to December 2015. PARTICIPANTS/MATERIALS, SETTING, METHODS Women aged 30–44 years, trying to conceive
ISSN:	0268-1161 1460-2350 1460-2350
DOI:	10.1093/humrep/deac027