Brain partial volume correction with point spreading function reconstruction in high-resolution digital PET: comparison with an MR-based method in FDG imaging

Objective In quantitative positron emission tomography (PET) of the brain, partial volume effect due mainly to the finite spatial resolution of the PET scanner (> 3 mm full width at half maximum [FWHM]) is a primary source of error in the measurement of tracer uptake, especially in small structur...

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Veröffentlicht in:	Annals of nuclear medicine 2022-08, Vol.36 (8), p.717-727
Hauptverfasser:	Ibaraki, Masanobu, Matsubara, Keisuke, Shinohara, Yuki, Shidahara, Miho, Sato, Kaoru, Yamamoto, Hiroyuki, Kinoshita, Toshibumi
Format:	Artikel
Sprache:	eng
Schlagworte:	Algorithms Brain Brain - diagnostic imaging Cerebral cortex Computed tomography Digital imaging Error analysis Field of view Fluorodeoxyglucose F18 Humans Image Processing, Computer-Assisted - methods Imaging Magnetic resonance imaging Magnetic Resonance Imaging - methods Medical imaging Medicine Medicine & Public Health Neuroimaging Nuclear Medicine Original Original Article Phantoms, Imaging Point spread functions Positron emission Positron emission tomography Positron Emission Tomography Computed Tomography Positron-Emission Tomography - methods Radiology Reconstruction Scanners Spatial discrimination Spatial resolution Tomography
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Zusammenfassung:	Objective In quantitative positron emission tomography (PET) of the brain, partial volume effect due mainly to the finite spatial resolution of the PET scanner (> 3 mm full width at half maximum [FWHM]) is a primary source of error in the measurement of tracer uptake, especially in small structures such as the cerebral cortex (typically
ISSN:	0914-7187 1864-6433
DOI:	10.1007/s12149-022-01753-5