Forty‐eight hours of normothermic kidney preservation applying urine recirculation

Kidney transplantation is limited due to the organ scarcity and the large discrepancy between transplantable organs and patients on the waiting list. Ex‐situ normothermic kidney preservation has been studied extensively as a tool to enlarge the donor pool and to enable viability assessment. Urine re...

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Veröffentlicht in:Artificial organs 2022-04, Vol.46 (4), p.710-714
Hauptverfasser: Weissenbacher, Annemarie, Messner, Franka, Gasteiger, Silvia, Soleiman, Afschin, Öfner, Dietmar, Schneeberger, Stefan
Format: Artikel
Sprache:eng
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Zusammenfassung:Kidney transplantation is limited due to the organ scarcity and the large discrepancy between transplantable organs and patients on the waiting list. Ex‐situ normothermic kidney preservation has been studied extensively as a tool to enlarge the donor pool and to enable viability assessment. Urine recirculation, for volume control, was applied to perfuse a discarded human kidney for 48 hours. Long‐term kidney NMP was feasible under stable hemodynamic conditions with a physiological acid‐base‐balance and an intact histological morphology of the organ.
ISSN:0160-564X
1525-1594
DOI:10.1111/aor.14160