Additional burden of iron deficiency in heart failure patients beyond the cardio‐renal anaemia syndrome: findings from the BIOSTAT‐CHF study

Aims Whereas the combination of anaemia and chronic kidney disease (CKD) has been extensively studied in patients with heart failure (HF), the contribution of iron deficiency (ID) to this dysfunctional interplay is unknown. We aimed to assess clinical associates and pathophysiological pathways relat...

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Veröffentlicht in:	European journal of heart failure 2022-01, Vol.24 (1), p.192-204
Hauptverfasser:	Alnuwaysir, Ridha I.S., Grote Beverborg, Niels, Hoes, Martijn F., Markousis‐Mavrogenis, George, Gomez, Karla A., Wal, Haye H., Cleland, John G.F., Dickstein, Kenneth, Lang, Chim C., Ng, Leong L., Ponikowski, Piotr, Anker, Stefan D., Veldhuisen, Dirk J., Voors, Adriaan A., Meer, Peter
Format:	Artikel
Sprache:	eng
Schlagworte:	Anaemia Anemia - complications Anemia - epidemiology Anemia, Iron-Deficiency - complications Anemia, Iron-Deficiency - epidemiology Biomarkers Cardio-Renal Syndrome - epidemiology Cardiorenal Chronic kidney disease Comorbidities Heart failure Heart Failure - complications Heart Failure - epidemiology Humans Iron Deficiencies Iron deficiency Male Quality of Life
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Zusammenfassung:	Aims Whereas the combination of anaemia and chronic kidney disease (CKD) has been extensively studied in patients with heart failure (HF), the contribution of iron deficiency (ID) to this dysfunctional interplay is unknown. We aimed to assess clinical associates and pathophysiological pathways related to ID in this multimorbid syndrome. Methods and results We studied 2151 patients with HF from the BIOSTAT‐CHF cohort. Patients were stratified based on ID (transferrin saturation
ISSN:	1388-9842 1879-0844
DOI:	10.1002/ejhf.2393