Comparison of pregnancy outcomes in Dutch kidney recipients with and without calcineurin inhibitor exposure: a retrospective study

Summary Within pregnancies occurring between 1986 and 2017 in Dutch kidney transplant recipients (KTR), we retrospectively compared short‐term maternal and foetal outcomes between patients on calcineurin inhibitor (CNI) based (CNI+) and CNI‐free immunosuppression (CNI−). We identified 129 CNI+ and 1...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Transplant international 2021-12, Vol.34 (12), p.2669-2679
Hauptverfasser:	Koenjer, Lisanne M., Meinderts, Jildau R., Heijden, Olivier W. H., Lely, Titia, Jong, Margriet F. C., Molen, Renate G., Hamersvelt, Henk W., Bemelman, FJ, de Boer, M, Christiaans, MHL, Groenewout, M, Ganzevoort, W, Nurmohammed, SA, van Reekum, FE, Rischen‐Vos, J, Spaanderman, MEA, Sueters, M, Visser, W, de Vries, APJ
Format:	Artikel
Sprache:	eng
Schlagworte:	azathioprine Birth weight Body mass Body mass index Body size Calcineurin Calcineurin inhibitors Calcineurin Inhibitors - adverse effects Creatinine Demography Female Graft Rejection Humans Immunosuppression Immunosuppressive Agents - adverse effects Infant, Newborn Inhibitors Kidney Kidney transplantation Kidney Transplantation - adverse effects Kidney transplants Kidneys Low birth weight Netherlands Original Original : Clinical Research Postpartum Pregnancy Pregnancy Outcome Retrospective Studies Transplantation Transplants & implants
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Summary Within pregnancies occurring between 1986 and 2017 in Dutch kidney transplant recipients (KTR), we retrospectively compared short‐term maternal and foetal outcomes between patients on calcineurin inhibitor (CNI) based (CNI+) and CNI‐free immunosuppression (CNI−). We identified 129 CNI+ and 125 CNI− pregnancies in 177 KTR. Demographics differed with CNI+ having higher body mass index (P = 0.045), shorter transplant‐pregnancy interval (P
ISSN:	0934-0874 1432-2277
DOI:	10.1111/tri.14156