Clinical and immunological evaluation of cat‐allergic asthmatics living with or without a cat

Clinical and immunological evaluation of cat‐allergic asthmatics living with or without a cat

Background Characterising the clinical and immunological impact of daily cat exposure in cat‐allergic subjects with asthma who live with cats (WC) and those who do not (WoC) may provide understanding of the drivers of the allergic response. Methods Clinical and immunological characteristics (skin pr...

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Veröffentlicht in:Clinical and experimental allergy 2021-12, Vol.51 (12), p.1624-1633
Hauptverfasser: Wambre, Erik R., Farrington, Mary, Bajzik, Veronique, DeBerg, Hannah A., Ruddy, Marcella, DeVeaux, Michelle, Meier, Pretty, Robinson, David, Cantor, Matt, Huang, Chengrui, Orengo, Jamie M., Wang, Claire Q., Radin, Allen
Format: Artikel
Sprache:eng
Schlagworte:
Allergens
Allergies
Asthma
Asthma - diagnosis
basophil activation
cat allergy
CD4 antigen
Corticosteroids
Dander
Fel d 1
Glycoproteins
Humans
Hypersensitivity
Immunoglobulin E
Immunoglobulin G
immunoglobulins
Immunological tolerance
Immunology
Original
Pets
Respiratory function
Skin tests
Th2A cells
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Zusammenfassung:Background Characterising the clinical and immunological impact of daily cat exposure in cat‐allergic subjects with asthma who live with cats (WC) and those who do not (WoC) may provide understanding of the drivers of the allergic response. Methods Clinical and immunological characteristics (skin prick test, spirometry, symptom assessments, immunological markers) were compared between asthmatic subjects WC (n = 10) and WoC (n = 9). Results WC subjects had greater use of long‐acting beta agonists (p 
ISSN:0954-7894
1365-2222
1365-2222
DOI:10.1111/cea.14024