Frequent detection of monkeypox virus DNA in saliva, semen, and other clinical samples from 12 patients, Barcelona, Spain, May to June 2022

A monkeypox (MPX) outbreak has expanded worldwide since May 2022. We tested 147 clinical samples collected at different time points from 12 patients by real-time PCR. MPX DNA was detected in saliva from all cases, sometimes with high viral loads. Other samples were frequently positive: rectal swab (...

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Veröffentlicht in:	Euro surveillance : bulletin européen sur les maladies transmissibles 2022-07, Vol.27 (28)
Hauptverfasser:	Peiró-Mestres, Aida, Fuertes, Irene, Camprubí-Ferrer, Daniel, Marcos, María Ángeles, Vilella, Anna, Navarro, Mireia, Rodriguez-Elena, Laura, Riera, Josep, Català, Alba, Martínez, Miguel J, Blanco, Jose L
Format:	Artikel
Sprache:	eng
Schlagworte:	DNA, Viral - genetics Humans Monkeypox virus - isolation & purification Mpox (monkeypox) - diagnosis Mpox (monkeypox) - epidemiology Rapid Communication Saliva Semen Spain - epidemiology
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Beschreibung
Zusammenfassung:	A monkeypox (MPX) outbreak has expanded worldwide since May 2022. We tested 147 clinical samples collected at different time points from 12 patients by real-time PCR. MPX DNA was detected in saliva from all cases, sometimes with high viral loads. Other samples were frequently positive: rectal swab (11/12 cases), nasopharyngeal swab (10/12 cases), semen (7/9 cases), urine (9/12 cases) and faeces (8/12 cases). These results improve knowledge on virus shedding and the possible role of bodily fluids in disease transmission.
ISSN:	1560-7917 1025-496X 1560-7917
DOI:	10.2807/1560-7917.ES.2022.27.28.2200503