Generation of Novel Severe Acute Respiratory Syndrome Coronavirus 2 Variants on the B.1.1.7 Lineage in 3 Patients With Advanced Human Immunodeficiency Virus-1 Disease

The emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is of public health concern in case of vaccine escape. Described are 3 patients with advanced human immunodeficiency virus (HIV)-1 and chronic SARS-CoV-2 infection in whom there is evidence of selection and pe...

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Veröffentlicht in:Clinical infectious diseases 2022-11, Vol.75 (11), p.2016-2018
Hauptverfasser: Riddell, Anna C, Kele, Beatrix, Harris, Kathryn, Bible, Jon, Murphy, Maurice, Dakshina, Subathira, Storey, Nathaniel, Owoyemi, Dola, Pade, Corinna, Gibbons, Joseph M, Harrington, David, Alexander, Eliza, McKnight, Áine, Cutino-Moguel, Teresa
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Sprache:eng
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Zusammenfassung:The emergence of new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variants is of public health concern in case of vaccine escape. Described are 3 patients with advanced human immunodeficiency virus (HIV)-1 and chronic SARS-CoV-2 infection in whom there is evidence of selection and persistence of novel mutations that are associated with increased transmissibility and immune escape.
ISSN:1058-4838
1537-6591
DOI:10.1093/cid/ciac409