The effect of Ivermectin on cases of COVID-19
Ivermectin is an antiviral agent that has historically had a wide variety of uses. Recently, it has gained popularity in the mainstream media for use in treating and preventing COVID-19 infection, prompting high sales in veterinary grade Ivermectin. Studies are increasingly looking at Ivermectin as...
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Veröffentlicht in: | Cardiovascular revascularization medicine 2022-11, Vol.44, p.98-100 |
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Sprache: | eng |
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Zusammenfassung: | Ivermectin is an antiviral agent that has historically had a wide variety of uses. Recently, it has gained popularity in the mainstream media for use in treating and preventing COVID-19 infection, prompting high sales in veterinary grade Ivermectin. Studies are increasingly looking at Ivermectin as a possible agent for prevention and treatment of COVID-19, however further information is needed to assess efficacy and safety. Our project aimed to evaluate mortality differences in patients with COVID-19 infection who were prescribed Ivermectin vs. those not prescribed Ivermectin. Adult patients with active COVID-19 infection who were not prescribed Ivermectin (n = 797,285 Outpatient, n = 481,705 Inpatient, and n = 58,050 Intensive care unit), and those prescribed Ivermectin (n = 804 Outpatient, n = 1774 Inpatient, and n = 107 Intensive care unit) were evaluated. The cohorts were then evaluated for mortality comparing patients prescribed Ivermectin and those not prescribed Ivermectin in the Outpatient (7.7 % vs 2.2 %, P < 0.001), Inpatient not requiring Intensive Care (15.6 % vs 7.2 %, P ≤ 0.001), and Intensive care (20.6 % vs 19.6 %, P = 0.86) treatment settings.
•Ivermectin has been cited as a “wonder drug” with its wide range of activities of anti-microbial, anti-viral•Patients in all cohorts of our review had no significant mortality benefit with Ivermectin use.•Clinical trials evaluating the efficacy of Ivermectin for COVID-19 treatment are currently underway. |
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ISSN: | 1553-8389 1878-0938 |
DOI: | 10.1016/j.carrev.2022.06.004 |