Characterization of a bacteriocin-like substance produced by a vaginal Lactobacillus salivarius strain

A novel bacteriocin-like substance produced by vaginal Lactobacillus salivarius subsp. salivarius CRL 1328 with activity against Enterococcus faecalis, Enterococcus faecium, and Neisseria gonorrhoeae was characterized. The highest level of production of this heat-resistant peptide or protein occurre...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Veröffentlicht in:	Applied and environmental microbiology 1999-12, Vol.65 (12), p.5631-5635
Hauptverfasser:	OCANA, V. S, DE RUIZ HOLGADO, A. A. P, NADER-MACIAS, M. E
Format:	Artikel
Sprache:	eng
Schlagworte:	Bacteria Bacteriocins - biosynthesis Bacteriocins - pharmacology Bacteriology Biological and medical sciences Candida - drug effects Drug Resistance, Microbial Enterococcus faecalis Enterococcus faecalis - drug effects Enterococcus faecium Enterococcus faecium - drug effects Environmental and Public Health Microbiology Female Fundamental and applied biological sciences. Psychology Humans Kinetics Lactobacillus - growth & development Lactobacillus - isolation & purification Lactobacillus - metabolism Lactobacillus salivarius Microbial Sensitivity Tests Microbiology Neisseria gonorrhoeae Neisseria gonorrhoeae - drug effects Pathogenicity, virulence, toxins, bacteriocins, pyrogens, host-bacteria relations, miscellaneous strains Proteins Reproductive system Vagina - microbiology
Online-Zugang:	Volltext
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A novel bacteriocin-like substance produced by vaginal Lactobacillus salivarius subsp. salivarius CRL 1328 with activity against Enterococcus faecalis, Enterococcus faecium, and Neisseria gonorrhoeae was characterized. The highest level of production of this heat-resistant peptide or protein occurred during the late exponential phase. Its mode of action was shown to be bactericidal. L. salivarius subsp. salivarius CRL 1328 could be used for the design of a probiotic to prevent urogenital infections.
ISSN:	0099-2240 1098-5336
DOI:	10.1128/aem.65.12.5631-5635.1999