Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2

Protection and Waning of Natural and Hybrid Immunity to SARS-CoV-2

Investigators from Israel explored the effect of two vaccine doses, three vaccine doses, and previous SARS-CoV-2 infection (without vaccination and before or after vaccination) on subsequent SARS-CoV-2 infection and progression to severe illness. Previous immunity-conferring events (vaccination or i...

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Veröffentlicht in:The New England journal of medicine 2022-06, Vol.386 (23), p.2201-2212
Hauptverfasser: Goldberg, Yair, Mandel, Micha, Bar-On, Yinon M., Bodenheimer, Omri, Freedman, Laurence S., Ash, Nachman, Alroy-Preis, Sharon, Huppert, Amit, Milo, Ron
Format: Artikel
Sprache:eng
Schlagworte:
Coronavirus
Coronaviruses
COVID-19 vaccines
Immunity (Disease)
Infections
Infectious Disease
Original
Population
Severe acute respiratory syndrome coronavirus 2
Vaccination
Vaccines
Viral Infections
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Beschreibung
Zusammenfassung:Investigators from Israel explored the effect of two vaccine doses, three vaccine doses, and previous SARS-CoV-2 infection (without vaccination and before or after vaccination) on subsequent SARS-CoV-2 infection and progression to severe illness. Previous immunity-conferring events (vaccination or infection) were identified as being protective, but all protection waned with time.
ISSN:0028-4793
1533-4406
DOI:10.1056/NEJMoa2118946