Effect of intensive blood pressure control on subtypes of mild cognitive impairment and risk of progression from SPRINT study

Background To examine the effect of intensive blood pressure control on the occurrence of subtypes of mild cognitive impairment (MCI) and determine the risk of progression to dementia or death. Methods Secondary analysis of a randomized trial of community‐dwelling adults (≥50 years) with hypertensio...

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Veröffentlicht in:	Journal of the American Geriatrics Society (JAGS) 2022-05, Vol.70 (5), p.1384-1393
Hauptverfasser:	Gaussoin, Sarah A., Pajewski, Nicholas M., Chelune, Gordon, Cleveland, Maryjo L., Crowe, Michael G., Launer, Lenore J., Lerner, Alan J., Martindale‐Adams, Jennifer, Nichols, Linda O., Ogrocki, Paula K., Sachs, Bonnie C., Sink, Kaycee M., Supiano, Mark A., Wadley, Virginia G., Wilson, Valerie M., Wright, Clinton B., Williamson, Jeff D., Reboussin, David M., Rapp, Stephen R.
Format:	Artikel
Sprache:	eng
Schlagworte:	Aged Blood pressure Blood Pressure - physiology blood pressure control clinical trials Cognitive ability Cognitive Dysfunction - epidemiology Death Dementia Dementia - epidemiology Dementia disorders Disease Progression Female Humans Hypertension - complications Hypertension - drug therapy MCI (mild cognitive impairment) Proportional Hazards Models
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Zusammenfassung:	Background To examine the effect of intensive blood pressure control on the occurrence of subtypes of mild cognitive impairment (MCI) and determine the risk of progression to dementia or death. Methods Secondary analysis of a randomized trial of community‐dwelling adults (≥50 years) with hypertension. Participants were randomized to a systolic blood pressure (SBP) goal of
ISSN:	0002-8614 1532-5415
DOI:	10.1111/jgs.17583