A case of jejunal GIST revealed by hematemesis: Unusual situation

Gastrointestinal stromal tumors (GISTs) are rare tumors of the gastrointestinal (GI) tract, which can occur in majorly stomach, and rarely in the small intestine, rectum, and large intestine. We report a jejunal GIST presented with massive hematemesis in the current study. A 39-years-old male, without any underlying history, was presented to our center with the complaint of massive hematemesis. Given the unstable hemodynamics of the patient, an upper GI endoscopy was requested, associated with a large amount of blood in the duodenal bulb without any sign of bleeding. The patient was sent to the operation room, and after laparotomy, a mass was seen in the jejunum, revealed as GIST after pathological study. Small-intestine-related etiologies are rare conditions related to upper GI bleeding (UGIB). Jejunal GIST usually manifests as asymptomatic subepithelial mass and is associated with abdominal discomfort or GI bleeding. Sudden unset bleeding is a rare manifestation of jejunal GIST, but it can be associated with the emergency outcome and may need emergency intervention. UGIB can occur in jejunal GIST, which should be considered in the management of UGIB. •Gastrointestinal stromal tumors (GISTs) are rare tumors of the gastrointestinal (GI) tract.•GISTs are rarely found in the small intestine, compatible with abdominal discomfort.•Jejunal GISTs usually manifest as intestinal obstruction and abdominal pain.•Massive hematemesis is rare in jejunal GISTs and should be consider in the management of upper GI bleeding.