Comparative effects of mRNA vaccine booster and natural Omicron infection on the neutralizing antibody response

A recent report found that booster vaccination could significantly increase the neutralizing responses to all the variant of concern, including Omicron [1]. Other studies questioned whether a booster dose of vaccine is more effective than two doses in preventing symptomatic SARS-CoV-2 in pre-Omicron...

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Veröffentlicht in:The Journal of infection 2022-07, Vol.85 (1), p.e4-e6
Hauptverfasser: Dimeglio, Chloé, Migueres, Marion, Chapuy-Regaud, Sabine, Da-Silva, Isabelle, Jougla, Isabelle, Pradere, Claire, Porcheron, Marion, Martin-Blondel, Guillaume, Lougarre, Catherine, Herin, Fabrice, Izopet, Jacques
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container_issue 1
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container_title The Journal of infection
container_volume 85
creator Dimeglio, Chloé
Migueres, Marion
Chapuy-Regaud, Sabine
Da-Silva, Isabelle
Jougla, Isabelle
Pradere, Claire
Porcheron, Marion
Martin-Blondel, Guillaume
Lougarre, Catherine
Herin, Fabrice
Izopet, Jacques
description A recent report found that booster vaccination could significantly increase the neutralizing responses to all the variant of concern, including Omicron [1]. Other studies questioned whether a booster dose of vaccine is more effective than two doses in preventing symptomatic SARS-CoV-2 in pre-Omicron populations [2]. New waves of infection can occur in populations whose immunity is due to a prior infection and/or vaccination [3], while other studies indicate that Omicron overcomes the immunity provided by vaccination and/or infection with an earlier variant [4]. Public health policies can benefit from knowledge of the immune responses elicited by vaccination and natural infection.
doi_str_mv 10.1016/j.jinf.2022.05.001
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Other studies questioned whether a booster dose of vaccine is more effective than two doses in preventing symptomatic SARS-CoV-2 in pre-Omicron populations [2]. New waves of infection can occur in populations whose immunity is due to a prior infection and/or vaccination [3], while other studies indicate that Omicron overcomes the immunity provided by vaccination and/or infection with an earlier variant [4]. 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source MEDLINE; Access via ScienceDirect (Elsevier)
subjects Antibodies, Neutralizing
Antibodies, Viral
Antibody Formation
Human health and pathology
Humans
Letter to the Editor
Life Sciences
mRNA Vaccines
Vaccines, Synthetic
title Comparative effects of mRNA vaccine booster and natural Omicron infection on the neutralizing antibody response
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