Comparative effects of mRNA vaccine booster and natural Omicron infection on the neutralizing antibody response
A recent report found that booster vaccination could significantly increase the neutralizing responses to all the variant of concern, including Omicron [1]. Other studies questioned whether a booster dose of vaccine is more effective than two doses in preventing symptomatic SARS-CoV-2 in pre-Omicron...
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Veröffentlicht in: | The Journal of infection 2022-07, Vol.85 (1), p.e4-e6 |
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creator | Dimeglio, Chloé Migueres, Marion Chapuy-Regaud, Sabine Da-Silva, Isabelle Jougla, Isabelle Pradere, Claire Porcheron, Marion Martin-Blondel, Guillaume Lougarre, Catherine Herin, Fabrice Izopet, Jacques |
description | A recent report found that booster vaccination could significantly increase the neutralizing responses to all the variant of concern, including Omicron [1]. Other studies questioned whether a booster dose of vaccine is more effective than two doses in preventing symptomatic SARS-CoV-2 in pre-Omicron populations [2]. New waves of infection can occur in populations whose immunity is due to a prior infection and/or vaccination [3], while other studies indicate that Omicron overcomes the immunity provided by vaccination and/or infection with an earlier variant [4]. Public health policies can benefit from knowledge of the immune responses elicited by vaccination and natural infection. |
doi_str_mv | 10.1016/j.jinf.2022.05.001 |
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Other studies questioned whether a booster dose of vaccine is more effective than two doses in preventing symptomatic SARS-CoV-2 in pre-Omicron populations [2]. New waves of infection can occur in populations whose immunity is due to a prior infection and/or vaccination [3], while other studies indicate that Omicron overcomes the immunity provided by vaccination and/or infection with an earlier variant [4]. 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Other studies questioned whether a booster dose of vaccine is more effective than two doses in preventing symptomatic SARS-CoV-2 in pre-Omicron populations [2]. New waves of infection can occur in populations whose immunity is due to a prior infection and/or vaccination [3], while other studies indicate that Omicron overcomes the immunity provided by vaccination and/or infection with an earlier variant [4]. Public health policies can benefit from knowledge of the immune responses elicited by vaccination and natural infection.</description><subject>Antibodies, Neutralizing</subject><subject>Antibodies, Viral</subject><subject>Antibody Formation</subject><subject>Human health and pathology</subject><subject>Humans</subject><subject>Letter to the Editor</subject><subject>Life Sciences</subject><subject>mRNA Vaccines</subject><subject>Vaccines, Synthetic</subject><issn>0163-4453</issn><issn>1532-2742</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2022</creationdate><recordtype>article</recordtype><sourceid>EIF</sourceid><recordid>eNp9kVFrFDEUhYNY7Fr9Az5IXn2Y8SaZTDogwrKoFZYWij6HTOamm6WTLMnsQP31zbBa1IdCICE53-HkHkLeMagZsPbjvt774GoOnNcgawD2gqyYFLziquEvyaqIRNU0UpyT1znvAaATXfuKnAsphZKiXZG4iePBJDP5GSk6h3bKNDo63l6v6Wys9QFpH2OeMFETBhrMdEzmnt6M3qYYaElQGF9OZU07pAGPUxH4Xz7cFWLyfRweaMJ8iCHjG3LmzH3Gt7_3C_Lz65cfm6tqe_Pt-2a9rWxz2U1VZ5R1KCXruJRGMQZctsLangnRNB0CHwY2MM4uu9Y5V77b9ShUq1rJoQUlLsjnk-_h2I84WAxLKH1IfjTpQUfj9b8vwe_0XZx1B8VDLQYfTga7_7Cr9VYvd9AACCWamRUtP2nLRHJO6J4ABnqpSu_1UpVeqtIgdamqQO__TviE_OmmCD6dBFjmNHtMOluPweLgUxm5HqJ_zv8RQeSmeQ</recordid><startdate>20220701</startdate><enddate>20220701</enddate><creator>Dimeglio, Chloé</creator><creator>Migueres, Marion</creator><creator>Chapuy-Regaud, Sabine</creator><creator>Da-Silva, Isabelle</creator><creator>Jougla, Isabelle</creator><creator>Pradere, Claire</creator><creator>Porcheron, Marion</creator><creator>Martin-Blondel, Guillaume</creator><creator>Lougarre, Catherine</creator><creator>Herin, Fabrice</creator><creator>Izopet, Jacques</creator><general>Elsevier Ltd</general><general>WB Saunders</general><general>The British Infection Association. 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subjects | Antibodies, Neutralizing Antibodies, Viral Antibody Formation Human health and pathology Humans Letter to the Editor Life Sciences mRNA Vaccines Vaccines, Synthetic |
title | Comparative effects of mRNA vaccine booster and natural Omicron infection on the neutralizing antibody response |
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